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Depleting plasmacytoid dendritic cells reduces local type I interferon responses and disease activity in patients with cutaneous lupus.
Karnell JL, Wu Y, Mittereder N, Smith MA, Gunsior M, Yan L, Casey KA, Henault J, Riggs JM, Nicholson SM, Sanjuan MA, Vousden KA, Werth VP, Drappa J, Illei GG, Rees WA, Ratchford JN; VIB7734 Trial Investigators. Karnell JL, et al. Among authors: sanjuan ma. Sci Transl Med. 2021 May 26;13(595):eabf8442. doi: 10.1126/scitranslmed.abf8442. Sci Transl Med. 2021. PMID: 34039741 Clinical Trial.
Self-reactive IgE exacerbates interferon responses associated with autoimmunity.
Henault J, Riggs JM, Karnell JL, Liarski VM, Li J, Shirinian L, Xu L, Casey KA, Smith MA, Khatry DB, Izhak L, Clarke L, Herbst R, Ettinger R, Petri M, Clark MR, Mustelin T, Kolbeck R, Sanjuan MA. Henault J, et al. Among authors: sanjuan ma. Nat Immunol. 2016 Feb;17(2):196-203. doi: 10.1038/ni.3326. Epub 2015 Dec 21. Nat Immunol. 2016. PMID: 26692173 Free PMC article.
Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.
Panda SK, Facchinetti V, Voynova E, Hanabuchi S, Karnell JL, Hanna RN, Kolbeck R, Sanjuan MA, Ettinger R, Liu YJ. Panda SK, et al. Among authors: sanjuan ma. J Clin Invest. 2018 May 1;128(5):1873-1887. doi: 10.1172/JCI97333. Epub 2018 Apr 3. J Clin Invest. 2018. PMID: 29611821 Free PMC article.
Natural killer cell expression of Ki67 is associated with elevated serum IL-15, disease activity and nephritis in systemic lupus erythematosus.
Hudspeth K, Wang S, Wang J, Rahman S, Smith MA, Casey KA; Autoimmunity Molecular Team; Manna Z, Sanjuan M, Kolbeck R, Hasni S, Ettinger R, Siegel RM. Hudspeth K, et al. Among authors: sanjuan m. Clin Exp Immunol. 2019 May;196(2):226-236. doi: 10.1111/cei.13263. Epub 2019 Mar 19. Clin Exp Immunol. 2019. PMID: 30693467 Free PMC article.
Characterisation of anifrolumab, a fully human anti-interferon receptor antagonist antibody for the treatment of systemic lupus erythematosus.
Riggs JM, Hanna RN, Rajan B, Zerrouki K, Karnell JL, Sagar D, Vainshtein I, Farmer E, Rosenthal K, Morehouse C, de Los Reyes M, Schifferli K, Liang M, Sanjuan MA, Sims GP, Kolbeck R. Riggs JM, et al. Among authors: sanjuan ma. Lupus Sci Med. 2018 Apr 5;5(1):e000261. doi: 10.1136/lupus-2018-000261. eCollection 2018. Lupus Sci Med. 2018. PMID: 29644082 Free PMC article.
130 results