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Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens.
Morris JA, Caragine C, Daniloski Z, Domingo J, Barry T, Lu L, Davis K, Ziosi M, Glinos DA, Hao S, Mimitou EP, Smibert P, Roeder K, Katsevich E, Lappalainen T, Sanjana NE. Morris JA, et al. Among authors: sanjana ne. Science. 2023 May 19;380(6646):eadh7699. doi: 10.1126/science.adh7699. Epub 2023 May 19. Science. 2023. PMID: 37141313 Free PMC article.
Massively parallel Cas13 screens reveal principles for guide RNA design.
Wessels HH, Méndez-Mancilla A, Guo X, Legut M, Daniloski Z, Sanjana NE. Wessels HH, et al. Among authors: sanjana ne. Nat Biotechnol. 2020 Jun;38(6):722-727. doi: 10.1038/s41587-020-0456-9. Epub 2020 Mar 16. Nat Biotechnol. 2020. PMID: 32518401 Free PMC article.
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells.
Daniloski Z, Jordan TX, Wessels HH, Hoagland DA, Kasela S, Legut M, Maniatis S, Mimitou EP, Lu L, Geller E, Danziger O, Rosenberg BR, Phatnani H, Smibert P, Lappalainen T, tenOever BR, Sanjana NE. Daniloski Z, et al. Among authors: sanjana ne. Cell. 2021 Jan 7;184(1):92-105.e16. doi: 10.1016/j.cell.2020.10.030. Epub 2020 Oct 24. Cell. 2021. PMID: 33147445 Free PMC article.
Profiling the genetic determinants of chromatin accessibility with scalable single-cell CRISPR screens.
Liscovitch-Brauer N, Montalbano A, Deng J, Méndez-Mancilla A, Wessels HH, Moss NG, Kung CY, Sookdeo A, Guo X, Geller E, Jaini S, Smibert P, Sanjana NE. Liscovitch-Brauer N, et al. Among authors: sanjana ne. Nat Biotechnol. 2021 Oct;39(10):1270-1277. doi: 10.1038/s41587-021-00902-x. Epub 2021 Apr 29. Nat Biotechnol. 2021. PMID: 33927415 Free PMC article.
CRISPR in cancer biology and therapy.
Katti A, Diaz BJ, Caragine CM, Sanjana NE, Dow LE. Katti A, et al. Among authors: sanjana ne. Nat Rev Cancer. 2022 May;22(5):259-279. doi: 10.1038/s41568-022-00441-w. Epub 2022 Feb 22. Nat Rev Cancer. 2022. PMID: 35194172 Review.
A genome-scale screen for synthetic drivers of T cell proliferation.
Legut M, Gajic Z, Guarino M, Daniloski Z, Rahman JA, Xue X, Lu C, Lu L, Mimitou EP, Hao S, Davoli T, Diefenbach C, Smibert P, Sanjana NE. Legut M, et al. Among authors: sanjana ne. Nature. 2022 Mar;603(7902):728-735. doi: 10.1038/s41586-022-04494-7. Epub 2022 Mar 16. Nature. 2022. PMID: 35296855 Free PMC article.
74 results