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The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the transition to productive infection.
Sourvinos G, Morou A, Sanidas I, Codruta I, Ezell SA, Doxaki C, Kampranis SC, Kottakis F, Tsichlis PN. Sourvinos G, et al. Among authors: sanidas i. PLoS Pathog. 2014 May 15;10(5):e1004136. doi: 10.1371/journal.ppat.1004136. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24830456 Free PMC article.
Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation.
Nicolay BN, Danielian PS, Kottakis F, Lapek JD Jr, Sanidas I, Miles WO, Dehnad M, Tschöp K, Gierut JJ, Manning AL, Morris R, Haigis K, Bardeesy N, Lees JA, Haas W, Dyson NJ. Nicolay BN, et al. Among authors: sanidas i. Genes Dev. 2015 Sep 1;29(17):1875-89. doi: 10.1101/gad.264127.115. Epub 2015 Aug 27. Genes Dev. 2015. PMID: 26314710 Free PMC article.
Active RB causes visible changes in nuclear organization.
Krishnan B, Yasuhara T, Rumde P, Stanzione M, Lu C, Lee H, Lawrence MS, Zou L, Nieman LT, Sanidas I, Dyson NJ. Krishnan B, et al. Among authors: sanidas i. J Cell Biol. 2022 Mar 7;221(3):e202102144. doi: 10.1083/jcb.202102144. Epub 2022 Jan 12. J Cell Biol. 2022. PMID: 35019938 Free PMC article.
pRB Takes an EZ Path to a Repetitive Task.
Sanidas I, Dyson NJ. Sanidas I, et al. Mol Cell. 2016 Dec 15;64(6):1015-1017. doi: 10.1016/j.molcel.2016.11.035. Mol Cell. 2016. PMID: 27984740 Free article.
A Code of Mono-phosphorylation Modulates the Function of RB.
Sanidas I, Morris R, Fella KA, Rumde PH, Boukhali M, Tai EC, Ting DT, Lawrence MS, Haas W, Dyson NJ. Sanidas I, et al. Mol Cell. 2019 Mar 7;73(5):985-1000.e6. doi: 10.1016/j.molcel.2019.01.004. Epub 2019 Jan 30. Mol Cell. 2019. PMID: 30711375 Free PMC article.
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