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Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans.
Bhattacharya C, Sandinge AS, Bragg RA, Heijer M, Yan J, Andersson LC, Jurva U, Pelay-Gimeno M, Vaes WHJ, de Ligt RAF, Gränfors M, Amilon C, Lindstedt EL, Menakuru SR, Garkaviy P, Weidolf L, Gopaul VS. Bhattacharya C, et al. Among authors: sandinge as. Drug Metab Dispos. 2023 Apr;51(4):451-463. doi: 10.1124/dmd.122.001100. Epub 2023 Jan 13. Drug Metab Dispos. 2023. PMID: 36639243
Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates.
Harris KL, Thomson RES, Gumulya Y, Foley G, Carrera-Pacheco SE, Syed P, Janosik T, Sandinge AS, Andersson S, Jurva U, Bodén M, Gillam EMJ. Harris KL, et al. Among authors: sandinge as. Mol Biol Evol. 2022 Jun 2;39(6):msac116. doi: 10.1093/molbev/msac116. Mol Biol Evol. 2022. PMID: 35639613 Free PMC article.
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein.
Davies N, Hovdal D, Edmunds N, Nordberg P, Dahlén A, Dabkowska A, Arteta MY, Radulescu A, Kjellman T, Höijer A, Seeliger F, Holmedal E, Andihn E, Bergenhem N, Sandinge AS, Johansson C, Hultin L, Johansson M, Lindqvist J, Björsson L, Jing Y, Bartesaghi S, Lindfors L, Andersson S. Davies N, et al. Among authors: sandinge as. Mol Ther Nucleic Acids. 2021 Mar 13;24:369-384. doi: 10.1016/j.omtn.2021.03.008. eCollection 2021 Jun 4. Mol Ther Nucleic Acids. 2021. PMID: 33868782 Free PMC article.
12 results