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Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix.
Kay EJ, Paterson K, Riera-Domingo C, Sumpton D, Däbritz JHM, Tardito S, Boldrini C, Hernandez-Fernaud JR, Athineos D, Dhayade S, Stepanova E, Gjerga E, Neilson LJ, Lilla S, Hedley A, Koulouras G, McGregor G, Jamieson C, Johnson RM, Park M, Kirschner K, Miller C, Kamphorst JJ, Loayza-Puch F, Saez-Rodriguez J, Mazzone M, Blyth K, Zagnoni M, Zanivan S. Kay EJ, et al. Among authors: dhayade s. Nat Metab. 2022 Aug;4(8):1084. doi: 10.1038/s42255-022-00632-7. Nat Metab. 2022. PMID: 35927357 Free PMC article. No abstract available.
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix.
Kay EJ, Paterson K, Riera-Domingo C, Sumpton D, Däbritz JHM, Tardito S, Boldrini C, Hernandez-Fernaud JR, Athineos D, Dhayade S, Stepanova E, Gjerga E, Neilson LJ, Lilla S, Hedley A, Koulouras G, McGregor G, Jamieson C, Johnson RM, Park M, Kirschner K, Miller C, Kamphorst JJ, Loayza-Puch F, Saez-Rodriguez J, Mazzone M, Blyth K, Zagnoni M, Zanivan S. Kay EJ, et al. Among authors: dhayade s. Nat Metab. 2022 Jun;4(6):693-710. doi: 10.1038/s42255-022-00582-0. Epub 2022 Jun 27. Nat Metab. 2022. PMID: 35760868 Free PMC article.
Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function.
Campbell KJ, Mason SM, Winder ML, Willemsen RBE, Cloix C, Lawson H, Rooney N, Dhayade S, Sims AH, Blyth K, Tait SWG. Campbell KJ, et al. Among authors: dhayade s. Cell Death Differ. 2021 Sep;28(9):2589-2600. doi: 10.1038/s41418-021-00773-4. Epub 2021 Mar 31. Cell Death Differ. 2021. PMID: 33785871 Free PMC article.
Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice.
Humpton TJ, Nomura K, Weber J, Magnussen HM, Hock AK, Nixon C, Dhayade S, Stevenson D, Huang DT, Strathdee D, Blyth K, Vousden KH. Humpton TJ, et al. Among authors: dhayade s. Genes Dev. 2021 Jan 1;35(1-2):117-132. doi: 10.1101/gad.341875.120. Epub 2020 Dec 17. Genes Dev. 2021. PMID: 33334825 Free PMC article.
Formate induces a metabolic switch in nucleotide and energy metabolism.
Oizel K, Tait-Mulder J, Fernandez-de-Cossio-Diaz J, Pietzke M, Brunton H, Lilla S, Dhayade S, Athineos D, Blanco GR, Sumpton D, Mackay GM, Blyth K, Zanivan SR, Meiser J, Vazquez A. Oizel K, et al. Among authors: dhayade s. Cell Death Dis. 2020 May 4;11(5):310. doi: 10.1038/s41419-020-2523-z. Cell Death Dis. 2020. PMID: 32366892 Free PMC article.
A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing.
Hassan S, Purdie KJ, Wang J, Harwood CA, Proby CM, Pourreyron C, Mladkova N, Nagano A, Dhayade S, Athineos D, Caley M, Mannella V, Blyth K, Inman GJ, Leigh IM. Hassan S, et al. Among authors: dhayade s. Int J Mol Sci. 2019 Jul 12;20(14):3428. doi: 10.3390/ijms20143428. Int J Mol Sci. 2019. PMID: 31336867 Free PMC article.
Increased formate overflow is a hallmark of oxidative cancer.
Meiser J, Schuster A, Pietzke M, Vande Voorde J, Athineos D, Oizel K, Burgos-Barragan G, Wit N, Dhayade S, Morton JP, Dornier E, Sumpton D, Mackay GM, Blyth K, Patel KJ, Niclou SP, Vazquez A. Meiser J, et al. Among authors: dhayade s. Nat Commun. 2018 Apr 10;9(1):1368. doi: 10.1038/s41467-018-03777-w. Nat Commun. 2018. PMID: 29636461 Free PMC article.
21 results