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Pharmacological Elevation of Cellular Dihydrosphingomyelin Provides a Novel Antiviral Strategy against West Nile Virus Infection.
Jiménez de Oya N, San-Félix A, Casasampere M, Blázquez AB, Mingo-Casas P, Escribano-Romero E, Calvo-Pinilla E, Poderoso T, Casas J, Saiz JC, Pérez-Pérez MJ, Martín-Acebes MA. Jiménez de Oya N, et al. Among authors: san felix a. Antimicrob Agents Chemother. 2023 Apr 18;67(4):e0168722. doi: 10.1128/aac.01687-22. Epub 2023 Mar 15. Antimicrob Agents Chemother. 2023. PMID: 36920206 Free PMC article.
3'-Spiro nucleosides, a new class of specific human immunodeficiency virus type 1 inhibitors: synthesis and antiviral activity of [2'-5'-bis-O-(tert-butyldimethylsilyl)-beta-D-xylo- and -ribofuranose]-3'-spiro-5"-[4"-amino-1",2"-oxathiole 2",2"-dioxide] (TSAO) pyrimidine nucleosides.
Camarasa MJ, Pérez-Pérez MJ, San-Félix A, Balzarini J, De Clercq E. Camarasa MJ, et al. J Med Chem. 1992 Jul 24;35(15):2721-7. doi: 10.1021/jm00093a002. J Med Chem. 1992. PMID: 1495006
[2',5'-Bis-O-(tert-butyldimethylsilyl)]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) (TSAO) derivatives of purine and pyrimidinenucleosides as potent and selective inhibitors of human immunodeficiency virus type 1.
Balzarini J, Pérez-Pérez MJ, San-Félix A, Velazquez S, Camarasa MJ, De Clercq E. Balzarini J, et al. Antimicrob Agents Chemother. 1992 May;36(5):1073-80. doi: 10.1128/AAC.36.5.1073. Antimicrob Agents Chemother. 1992. PMID: 1510396 Free PMC article.
Novel TSAO derivatives modified at positions 3" and 4" of the spiro moiety.
Lobatón E, Velázquez S, San-Félix A, Chamorro C, Tuñón V, Esteban-Gamboa A, De Clercq E, Balzarini J, Camarasa MJ, Pérez-Pérez MJ. Lobatón E, et al. Nucleosides Nucleotides. 1999 Apr-May;18(4-5):675-6. doi: 10.1080/15257779908041536. Nucleosides Nucleotides. 1999. PMID: 10432663
73 results