Salvador JAR - Search Results

1

New BACE1 Chimeric Peptide Inhibitors Selectively Prevent AβPP-β Cleavage Decreasing Amyloid-β Production and Accumulation in Alzheimer's Disease Models.

Resende R, Ferreira-Marques M, Moreira P, Coimbra JRM, Baptista SJ, Isidoro C, Salvador JAR, Dinis TCP, Pereira CF, Santos AE. Resende R, et al. Among authors: salvador jar. J Alzheimers Dis. 2020;76(4):1317-1337. doi: 10.3233/JAD-200381. J Alzheimers Dis. 2020. PMID: 32597812

2

Synthesis and structure-activity relationship study of novel cytotoxic carbamate and N-acylheterocyclic bearing derivatives of betulin and betulinic acid.

Santos RC, Salvador JA, Marín S, Cascante M, Moreira JN, Dinis TC. Santos RC, et al. Bioorg Med Chem. 2010 Jun 15;18(12):4385-96. doi: 10.1016/j.bmc.2010.04.085. Epub 2010 Apr 29. Bioorg Med Chem. 2010. PMID: 20494586

3

Novel PARP-1 Inhibitor Scaffolds Disclosed by a Dynamic Structure-Based Pharmacophore Approach.

Baptista SJ, Silva MM, Moroni E, Meli M, Colombo G, Dinis TC, Salvador JA. Baptista SJ, et al. PLoS One. 2017 Jan 25;12(1):e0170846. doi: 10.1371/journal.pone.0170846. eCollection 2017. PLoS One. 2017. PMID: 28122037 Free PMC article.

4

Highlights in BACE1 Inhibitors for Alzheimer's Disease Treatment.

Coimbra JRM, Marques DFF, Baptista SJ, Pereira CMF, Moreira PI, Dinis TCP, Santos AE, Salvador JAR. Coimbra JRM, et al. Among authors: salvador jar. Front Chem. 2018 May 24;6:178. doi: 10.3389/fchem.2018.00178. eCollection 2018. Front Chem. 2018. PMID: 29881722 Free PMC article. Review.

5

An overview of glutaminyl cyclase inhibitors for Alzheimer's disease.

Coimbra JR, Sobral PJ, Santos AE, Moreira PI, Salvador JA. Coimbra JR, et al. Future Med Chem. 2019 Dec;11(24):3179-3194. doi: 10.4155/fmc-2019-0163. Future Med Chem. 2019. PMID: 31838899 Review.

6

Combining Virtual Screening Protocol and In Vitro Evaluation towards the Discovery of BACE1 Inhibitors.

Coimbra JRM, Baptista SJ, Dinis TCP, Silva MMC, Moreira PI, Santos AE, Salvador JAR. Coimbra JRM, et al. Among authors: salvador jar. Biomolecules. 2020 Apr 1;10(4):535. doi: 10.3390/biom10040535. Biomolecules. 2020. PMID: 32244832 Free PMC article.

7

A patent review of glutaminyl cyclase inhibitors (2004-present).

Coimbra JRM, Salvador JAR. Coimbra JRM, et al. Among authors: salvador jar. Expert Opin Ther Pat. 2021 Sep;31(9):809-836. doi: 10.1080/13543776.2021.1917549. Epub 2021 Jul 5. Expert Opin Ther Pat. 2021. PMID: 33896339 Review.

8

Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resistance and Strategies to Overcome Anti-Cancer Drug Resistance.

Leonardo-Sousa C, Carvalho AN, Guedes RA, Fernandes PMP, Aniceto N, Salvador JAR, Gama MJ, Guedes RC. Leonardo-Sousa C, et al. Among authors: salvador jar. Molecules. 2022 Mar 28;27(7):2201. doi: 10.3390/molecules27072201. Molecules. 2022. PMID: 35408601 Free PMC article. Review.

9

MDM2-Based Proteolysis-Targeting Chimeras (PROTACs): An Innovative Drug Strategy for Cancer Treatment.

Vicente ATS, Salvador JAR. Vicente ATS, et al. Among authors: salvador jar. Int J Mol Sci. 2022 Sep 21;23(19):11068. doi: 10.3390/ijms231911068. Int J Mol Sci. 2022. PMID: 36232374 Free PMC article. Review.

10

Highlights in USP7 inhibitors for cancer treatment.

Oliveira RI, Guedes RA, Salvador JAR. Oliveira RI, et al. Among authors: salvador jar. Front Chem. 2022 Sep 15;10:1005727. doi: 10.3389/fchem.2022.1005727. eCollection 2022. Front Chem. 2022. PMID: 36186590 Free PMC article. Review.

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