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C3d-Targeted factor H inhibits tissue complement in disease models and reduces glomerular injury without affecting circulating complement.
Liu F, Ryan ST, Fahnoe KC, Morgan JG, Cheung AE, Storek MJ, Best A, Chen HA, Locatelli M, Xu S, Schmidt E, Schmidt-Jiménez LF, Bieber K, Henderson JM, Lian CG, Verschoor A, Ludwig RJ, Benigni A, Remuzzi G, Salant DJ, Kalled SL, Thurman JM, Holers VM, Violette SM, Wawersik S. Liu F, et al. Among authors: salant dj. Mol Ther. 2024 Apr 3;32(4):1061-1079. doi: 10.1016/j.ymthe.2024.02.001. Epub 2024 Feb 20. Mol Ther. 2024. PMID: 38382529 Free article.
Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PLA2R1-associated membranous nephropathy.
Haddad G, Lorenzen JM, Ma H, de Haan N, Seeger H, Zaghrini C, Brandt S, Kölling M, Wegmann U, Kiss B, Pál G, Gál P, Wüthrich RP, Wuhrer M, Beck LH, Salant DJ, Lambeau G, Kistler AD. Haddad G, et al. Among authors: salant dj. J Clin Invest. 2021 Mar 1;131(5):e140453. doi: 10.1172/JCI140453. J Clin Invest. 2021. PMID: 33351779 Free PMC article.
Advancing Nephrology: Division Leaders Advise ASN.
Braden GL, Chapman A, Ellison DH, Gadegbeku CA, Gurley SB, Igarashi P, Kelepouris E, Moxey-Mims MM, Okusa MD, Plumb TJ, Quaggin SE, Salant DJ, Segal MS, Shankland SJ, Somlo S. Braden GL, et al. Among authors: salant dj. Clin J Am Soc Nephrol. 2021 Feb 8;16(2):319-327. doi: 10.2215/CJN.01550220. Epub 2020 Aug 12. Clin J Am Soc Nephrol. 2021. PMID: 32792352 Free PMC article.
Complement Deficiencies Result in Surrogate Pathways of Complement Activation in Novel Polygenic Lupus-like Models of Kidney Injury.
Skopelja-Gardner S, Colonna L, Hermanson P, Sun X, Tanaka L, Tai J, Nguyen Y, Snyder JM, Alpers CE, Hudkins KL, Salant DJ, Peng Y, Elkon KB. Skopelja-Gardner S, et al. Among authors: salant dj. J Immunol. 2020 May 15;204(10):2627-2640. doi: 10.4049/jimmunol.1901473. Epub 2020 Apr 1. J Immunol. 2020. PMID: 32238460 Free PMC article.
Loss of Roundabout Guidance Receptor 2 (Robo2) in Podocytes Protects Adult Mice from Glomerular Injury by Maintaining Podocyte Foot Process Structure.
Pisarek-Horowitz A, Fan X, Kumar S, Rasouly HM, Sharma R, Chen H, Coser K, Bluette CT, Hirenallur-Shanthappa D, Anderson SR, Yang H, Beck LH Jr, Bonegio RG, Henderson JM, Berasi SP, Salant DJ, Lu W. Pisarek-Horowitz A, et al. Among authors: salant dj. Am J Pathol. 2020 Apr;190(4):799-816. doi: 10.1016/j.ajpath.2019.12.009. Epub 2020 Mar 24. Am J Pathol. 2020. PMID: 32220420 Free PMC article.
166 results