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Colchicine exerts anti-atherosclerotic and -plaque-stabilizing effects targeting foam cell formation.
Schwarz N, Fernando S, Chen YC, Salagaras T, Rao SR, Liyanage S, Williamson AE, Toledo-Flores D, Dimasi C, Sargeant TJ, Manavis J, Eddy E, Kanellakis P, Thompson PL, Tan JTM, Snel MF, Bursill CA, Nicholls SJ, Peter K, Psaltis PJ. Schwarz N, et al. Among authors: salagaras t. FASEB J. 2023 Apr;37(4):e22846. doi: 10.1096/fj.202201469R. FASEB J. 2023. PMID: 36856983
Eukaryotic elongation factor 2 kinase regulates foam cell formation via translation of CD36.
Fernando S, Salagaras T, Schwarz N, Sandeman L, Tan JTM, Xie J, Zareh J, Jensen K, Williamson A, Dimasi C, Chhay P, Toledo-Flores D, Long A, Manavis J, Worthington M, Fitridge R, Di Bartolo BA, Bursill CA, Nicholls SJ, Proud CG, Psaltis PJ. Fernando S, et al. Among authors: salagaras t. FASEB J. 2022 Feb;36(2):e22154. doi: 10.1096/fj.202101034R. FASEB J. 2022. PMID: 35032419
Assessing the Impact of Colchicine on Coronary Plaque Phenotype After Myocardial Infarction with Optical Coherence Tomography: Rationale and Design of the COCOMO-ACS Study.
Montarello NJ, Singh K, Sinhal A, Wong DTL, Alcock R, Rajendran S, Dautov R, Barlis P, Patel S, Nidorf SM, Thompson PL, Salagaras T, Butters J, Nerlekar N, Di Giovanni G, Ottaway JL, Nicholls SJ, Psaltis PJ. Montarello NJ, et al. Among authors: salagaras t. Cardiovasc Drugs Ther. 2022 Dec;36(6):1175-1186. doi: 10.1007/s10557-021-07240-9. Epub 2021 Aug 25. Cardiovasc Drugs Ther. 2022. PMID: 34432196 Free PMC article. Clinical Trial.