Sakmar TP - Search Results

1

Sakmar TP. Sakmar TP. Nat Genet. 2000 Jul;25(3):245-6. doi: 10.1038/76976. Nat Genet. 2000. PMID: 10888860 Review. No abstract available.

2

Recurrent activating mutations of G-protein-coupled receptor CYSLTR2 in uveal melanoma.

Moore AR, Ceraudo E, Sher JJ, Guan Y, Shoushtari AN, Chang MT, Zhang JQ, Walczak EG, Kazmi MA, Taylor BS, Huber T, Chi P, Sakmar TP, Chen Y. Moore AR, et al. Among authors: sakmar tp. Nat Genet. 2016 Jun;48(6):675-80. doi: 10.1038/ng.3549. Epub 2016 Apr 18. Nat Genet. 2016. PMID: 27089179 Free PMC article.

3

Pharmacology: Inside-out receptor inhibition.

Sakmar TP, Huber T. Sakmar TP, et al. Nature. 2016 Dec 15;540(7633):344-345. doi: 10.1038/nature20486. Epub 2016 Dec 7. Nature. 2016. PMID: 27926728 No abstract available.

4

Combined Inhibition of Gα_q and MEK Enhances Therapeutic Efficacy in Uveal Melanoma.

Hitchman TD, Bayshtok G, Ceraudo E, Moore AR, Lee C, Jia R, Wang N, Pachai MR, Shoushtari AN, Francis JH, Guan Y, Chen J, Chang MT, Taylor BS, Sakmar TP, Huber T, Chi P, Chen Y. Hitchman TD, et al. Among authors: sakmar tp. Clin Cancer Res. 2021 Mar 1;27(5):1476-1490. doi: 10.1158/1078-0432.CCR-20-2860. Epub 2020 Nov 23. Clin Cancer Res. 2021. PMID: 33229459 Free PMC article.

5

Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling.

Ceraudo E, Horioka M, Mattheisen JM, Hitchman TD, Moore AR, Kazmi MA, Chi P, Chen Y, Sakmar TP, Huber T. Ceraudo E, et al. Among authors: sakmar tp. J Biol Chem. 2021 Jan-Jun;296:100163. doi: 10.1074/jbc.RA120.015352. Epub 2020 Dec 11. J Biol Chem. 2021. PMID: 33288675 Free PMC article.

6

Bioorthogonal fluorescent labeling of functional G-protein-coupled receptors.

Tian H, Naganathan S, Kazmi MA, Schwartz TW, Sakmar TP, Huber T. Tian H, et al. Among authors: sakmar tp. Chembiochem. 2014 Aug 18;15(12):1820-9. doi: 10.1002/cbic.201402193. Epub 2014 Jul 18. Chembiochem. 2014. PMID: 25045132 Free PMC article.

7

Chemical biology methods for investigating G protein-coupled receptor signaling.

Huber T, Sakmar TP. Huber T, et al. Among authors: sakmar tp. Chem Biol. 2014 Sep 18;21(9):1224-37. doi: 10.1016/j.chembiol.2014.08.009. Chem Biol. 2014. PMID: 25237865 Review.

8

FRET sensors reveal the retinal entry pathway in the G protein-coupled receptor rhodopsin.

Tian H, Gunnison KM, Kazmi MA, Sakmar TP, Huber T. Tian H, et al. Among authors: sakmar tp. iScience. 2022 Mar 11;25(4):104060. doi: 10.1016/j.isci.2022.104060. eCollection 2022 Apr 15. iScience. 2022. PMID: 35355518 Free PMC article.

9

Escaping the flatlands: new approaches for studying the dynamic assembly and activation of GPCR signaling complexes.

Huber T, Sakmar TP. Huber T, et al. Among authors: sakmar tp. Trends Pharmacol Sci. 2011 Jul;32(7):410-9. doi: 10.1016/j.tips.2011.03.004. Epub 2011 Apr 15. Trends Pharmacol Sci. 2011. PMID: 21497404 Free PMC article. Review.

10

Site-specific labeling of genetically encoded azido groups for multicolor, single-molecule fluorescence imaging of GPCRs.

Tian H, Sakmar TP, Huber T. Tian H, et al. Among authors: sakmar tp. Methods Cell Biol. 2013;117:267-303. doi: 10.1016/B978-0-12-408143-7.00015-3. Methods Cell Biol. 2013. PMID: 24143983

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