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Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice.
Sci Adv. 2020 Nov 4;6(45):eabd3233. doi: 10.1126/sciadv.abd3233. Print 2020 Nov.
Sci Adv. 2020.
PMID: 33148654
Free PMC article.
Protecting-Group-Mediated Diastereoselective Synthesis of C4'-Methylated Uridine Analogs and Their Activity against the Human Respiratory Syncytial Virus.
Köllmann C, Sake SM, Jones PG, Pietschmann T, Werz DB.
Köllmann C, et al. Among authors: sake sm.
J Org Chem. 2020 Mar 20;85(6):4267-4278. doi: 10.1021/acs.joc.9b03425. Epub 2020 Feb 26.
J Org Chem. 2020.
PMID: 32036652
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Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry.
Blockus S, Sake SM, Wetzke M, Grethe C, Graalmann T, Pils M, Le Goffic R, Galloux M, Prochnow H, Rox K, Hüttel S, Rupcic Z, Wiegmann B, Dijkman R, Rameix-Welti MA, Eléouët JF, Duprex WP, Thiel V, Hansen G, Brönstrup M, Haid S, Pietschmann T.
Blockus S, et al. Among authors: sake sm.
Antiviral Res. 2020 May;177:104774. doi: 10.1016/j.antiviral.2020.104774. Epub 2020 Mar 18.
Antiviral Res. 2020.
PMID: 32197980
Free article.
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A condensate-hardening drug blocks RSV replication in vivo.
Risso-Ballester J, Galloux M, Cao J, Le Goffic R, Hontonnou F, Jobart-Malfait A, Desquesnes A, Sake SM, Haid S, Du M, Zhang X, Zhang H, Wang Z, Rincheval V, Zhang Y, Pietschmann T, Eléouët JF, Rameix-Welti MA, Altmeyer R.
Risso-Ballester J, et al. Among authors: sake sm.
Nature. 2021 Jul;595(7868):596-599. doi: 10.1038/s41586-021-03703-z. Epub 2021 Jul 7.
Nature. 2021.
PMID: 34234347
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Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor.
Sake SM, Zhang X, Rajak MK, Urbanek-Quaing M, Carpentier A, Gunesch AP, Grethe C, Matthaei A, Rückert J, Galloux M, Larcher T, Le Goffic R, Hontonnou F, Chatterjee AK, Johnson K, Morwood K, Rox K, Elgaher WAM, Huang J, Wetzke M, Hansen G, Fischer N, Eléouët JF, Rameix-Welti MA, Hirsch AKH, Herold E, Empting M, Lauber C, Schulz TF, Krey T, Haid S, Pietschmann T.
Sake SM, et al.
Nat Commun. 2024 Feb 8;15(1):1173. doi: 10.1038/s41467-024-45241-y.
Nat Commun. 2024.
PMID: 38332002
Free PMC article.
Review.
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Repurposing screen identifies novel candidates for broad-spectrum coronavirus antivirals and druggable host targets.
Haid S, Matthaei A, Winkler M, Sake SM, Gunesch AP, Milke V, Köhler NM, Rückert J, Vieyres G, Kühl D, Nguyen T-T, Göhl M, Lasswitz L, Zapatero-Belinchón FJ, Brogden G, Gerold G, Wiegmann B, Bilitewski U, Brown RJP, Brönstrup M, Schulz TF, Pietschmann T.
Haid S, et al. Among authors: sake sm.
Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0121023. doi: 10.1128/aac.01210-23. Epub 2024 Feb 6.
Antimicrob Agents Chemother. 2024.
PMID: 38319076
Free PMC article.
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Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages.
Sake SM, Kosch C, Blockus S, Haid S, Gunesch AP, Zhang X, Friesland M, Trummer SB, Grethe C, Kühnel A, Rückert J, Duprex WP, Huang J, Rameix-Welti MA, Empting M, Fischer N, Hirsch AKH, Schulz TF, Pietschmann T.
Sake SM, et al.
Antimicrob Agents Chemother. 2022 Dec 20;66(12):e0103222. doi: 10.1128/aac.01032-22. Epub 2022 Nov 8.
Antimicrob Agents Chemother. 2022.
PMID: 36346232
Free PMC article.
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