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Cell response analysis in SARS-CoV-2 infected bronchial organoids.
Sano E, Suzuki T, Hashimoto R, Itoh Y, Sakamoto A, Sakai Y, Saito A, Okuzaki D, Motooka D, Muramoto Y, Noda T, Takasaki T, Sakuragi JI, Minami S, Kobayashi T, Yamamoto T, Matsumura Y, Nagao M, Okamoto T, Takayama K. Sano E, et al. Among authors: sakai y. Commun Biol. 2022 May 30;5(1):516. doi: 10.1038/s42003-022-03499-2. Commun Biol. 2022. PMID: 35637255 Free PMC article.
Characterization of SPP inhibitors suppressing propagation of HCV and protozoa.
Hirano J, Okamoto T, Sugiyama Y, Suzuki T, Kusakabe S, Tokunaga M, Fukuhara T, Sasai M, Tougan T, Matsunaga Y, Yamashita K, Sakai Y, Yamamoto M, Horii T, Standley DM, Moriishi K, Moriya K, Koike K, Matsuura Y. Hirano J, et al. Among authors: sakai y. Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10782-E10791. doi: 10.1073/pnas.1712484114. Epub 2017 Nov 29. Proc Natl Acad Sci U S A. 2017. PMID: 29187532 Free PMC article.
Hepatitis C virus modulates signal peptide peptidase to alter host protein processing.
Hirano J, Yoshio S, Sakai Y, Songling L, Suzuki T, Itoh Y, Zhang H, Chen DV, Haga S, Oomori H, Kodama T, Maeda Y, Ono Y, Takahashi Y, Standley DM, Yamamoto M, Moriishi K, Moriya K, Kanto T, Takehara T, Koike K, Matsuura Y, Okamoto T. Hirano J, et al. Among authors: sakai y. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2026184118. doi: 10.1073/pnas.2026184118. Proc Natl Acad Sci U S A. 2021. PMID: 34035171 Free PMC article.
Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2.
Higuchi Y, Suzuki T, Arimori T, Ikemura N, Mihara E, Kirita Y, Ohgitani E, Mazda O, Motooka D, Nakamura S, Sakai Y, Itoh Y, Sugihara F, Matsuura Y, Matoba S, Okamoto T, Takagi J, Hoshino A. Higuchi Y, et al. Among authors: sakai y. Nat Commun. 2021 Jun 21;12(1):3802. doi: 10.1038/s41467-021-24013-y. Nat Commun. 2021. PMID: 34155214 Free PMC article.
SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication.
Miyamoto Y, Itoh Y, Suzuki T, Tanaka T, Sakai Y, Koido M, Hata C, Wang CX, Otani M, Moriishi K, Tachibana T, Kamatani Y, Yoneda Y, Okamoto T, Oka M. Miyamoto Y, et al. Among authors: sakai y. Commun Biol. 2022 May 19;5(1):483. doi: 10.1038/s42003-022-03427-4. Commun Biol. 2022. PMID: 35590097 Free PMC article.
SARS-CoV-2 ORF8 is a viral cytokine regulating immune responses.
Kohyama M, Suzuki T, Nakai W, Ono C, Matsuoka S, Iwatani K, Liu Y, Sakai Y, Nakagawa A, Tomii K, Ohmura K, Okada M, Matsuura Y, Ohshima S, Maeda Y, Okamoto T, Arase H. Kohyama M, et al. Among authors: sakai y. Int Immunol. 2023 Jan 21;35(1):43-52. doi: 10.1093/intimm/dxac044. Int Immunol. 2023. PMID: 36053553 Free PMC article.
An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models.
Urano E, Itoh Y, Suzuki T, Sasaki T, Kishikawa JI, Akamatsu K, Higuchi Y, Sakai Y, Okamura T, Mitoma S, Sugihara F, Takada A, Kimura M, Nakao S, Hirose M, Sasaki T, Koketsu R, Tsuji S, Yanagida S, Shioda T, Hara E, Matoba S, Matsuura Y, Kanda Y, Arase H, Okada M, Takagi J, Kato T, Hoshino A, Yasutomi Y, Saito A, Okamoto T. Urano E, et al. Among authors: sakai y. Sci Transl Med. 2023 Aug 30;15(711):eadi2623. doi: 10.1126/scitranslmed.adi2623. Epub 2023 Aug 30. Sci Transl Med. 2023. PMID: 37647387
4,489 results