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CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory.
Kidani Y, Nogami W, Yasumizu Y, Kawashima A, Tanaka A, Sonoda Y, Tona Y, Nashiki K, Matsumoto R, Hagiwara M, Osaki M, Dohi K, Kanazawa T, Ueyama A, Yoshikawa M, Yoshida T, Matsumoto M, Hojo K, Shinonome S, Yoshida H, Hirata M, Haruna M, Nakamura Y, Motooka D, Okuzaki D, Sugiyama Y, Kinoshita M, Okuno T, Kato T, Hatano K, Uemura M, Imamura R, Yokoi K, Tanemura A, Shintani Y, Kimura T, Nonomura N, Wada H, Mori M, Doki Y, Ohkura N, Sakaguchi S. Kidani Y, et al. Among authors: sakaguchi s. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2114282119. doi: 10.1073/pnas.2114282119. Proc Natl Acad Sci U S A. 2022. PMID: 35140181 Free PMC article.
A novel modifier of regulatory T cells.
Ohkura N, Sakaguchi S. Ohkura N, et al. Among authors: sakaguchi s. Nat Immunol. 2009 Jul;10(7):685-6. doi: 10.1038/ni0709-685. Nat Immunol. 2009. PMID: 19536192
CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2.
Okamura T, Fujio K, Shibuya M, Sumitomo S, Shoda H, Sakaguchi S, Yamamoto K. Okamura T, et al. Among authors: sakaguchi s. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13974-9. doi: 10.1073/pnas.0906872106. Epub 2009 Aug 4. Proc Natl Acad Sci U S A. 2009. PMID: 19666526 Free PMC article.
Regulatory T cells in tumor immunity.
Nishikawa H, Sakaguchi S. Nishikawa H, et al. Among authors: sakaguchi s. Int J Cancer. 2010 Aug 15;127(4):759-67. doi: 10.1002/ijc.25429. Int J Cancer. 2010. PMID: 20518016 Free article. Review.
Foxo1 and Foxo3 help Foxp3.
Ohkura N, Sakaguchi S. Ohkura N, et al. Among authors: sakaguchi s. Immunity. 2010 Dec 14;33(6):835-7. doi: 10.1016/j.immuni.2010.12.004. Immunity. 2010. PMID: 21168774 Free article. No abstract available.
1,197 results