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Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.
Lacampagne A, Liu X, Reiken S, Bussiere R, Meli AC, Lauritzen I, Teich AF, Zalk R, Saint N, Arancio O, Bauer C, Duprat F, Briggs CA, Chakroborty S, Stutzmann GE, Shelanski ML, Checler F, Chami M, Marks AR. Lacampagne A, et al. Among authors: saint n. Acta Neuropathol. 2017 Nov;134(5):749-767. doi: 10.1007/s00401-017-1733-7. Epub 2017 Jun 19. Acta Neuropathol. 2017. PMID: 28631094 Free article.
Concomitant systolic and diastolic alterations during chronic hypertension in pig.
Jozwiak M, Meli AC, Melka J, Rienzo M, d'Anglemont de Tassigny A, Saint N, Bizé A, Sambin L, Scheuermann V, Cazorla O, Hittinger L, Berdeaux A, Su JB, Bouhemad B, Lacampagne A, Ghaleh B. Jozwiak M, et al. Among authors: saint n. J Mol Cell Cardiol. 2019 Jun;131:155-163. doi: 10.1016/j.yjmcc.2019.04.027. Epub 2019 Apr 30. J Mol Cell Cardiol. 2019. PMID: 31051181
Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation.
Matecki S, Dridi H, Jung B, Saint N, Reiken SR, Scheuermann V, Mrozek S, Santulli G, Umanskaya A, Petrof BJ, Jaber S, Marks AR, Lacampagne A. Matecki S, et al. Among authors: saint n. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9069-74. doi: 10.1073/pnas.1609707113. Epub 2016 Jul 25. Proc Natl Acad Sci U S A. 2016. PMID: 27457930 Free PMC article.
ANT-VDAC1 interaction is direct and depends on ANT isoform conformation in vitro.
Allouche M, Pertuiset C, Robert JL, Martel C, Veneziano R, Henry C, dein OS, Saint N, Brenner C, Chopineau J. Allouche M, et al. Among authors: saint n. Biochem Biophys Res Commun. 2012 Dec 7;429(1-2):12-7. doi: 10.1016/j.bbrc.2012.10.108. Epub 2012 Nov 3. Biochem Biophys Res Commun. 2012. PMID: 23131554
56 results