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LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses.
Li P, Hu M, Wang C, Feng X, Zhao Z, Yang Y, Sahoo N, Gu M, Yang Y, Xiao S, Sah R, Cover TL, Chou J, Geha R, Benavides F, Hume RI, Xu H. Li P, et al. Among authors: sahoo n. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):29155-29165. doi: 10.1073/pnas.2016539117. Epub 2020 Nov 2. Proc Natl Acad Sci U S A. 2020. PMID: 33139539 Free PMC article.
Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse models.
Yu L, Zhang X, Yang Y, Li D, Tang K, Zhao Z, He W, Wang C, Sahoo N, Converso-Baran K, Davis CS, Brooks SV, Bigot A, Calvo R, Martinez NJ, Southall N, Hu X, Marugan J, Ferrer M, Xu H. Yu L, et al. Among authors: sahoo n. Sci Adv. 2020 Feb 7;6(6):eaaz2736. doi: 10.1126/sciadv.aaz2736. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128386 Free PMC article.
Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca2+ Efflux Channel in the Tubulovesicle.
Sahoo N, Gu M, Zhang X, Raval N, Yang J, Bekier M, Calvo R, Patnaik S, Wang W, King G, Samie M, Gao Q, Sahoo S, Sundaresan S, Keeley TM, Wang Y, Marugan J, Ferrer M, Samuelson LC, Merchant JL, Xu H. Sahoo N, et al. Among authors: sahoo s. Dev Cell. 2017 May 8;41(3):262-273.e6. doi: 10.1016/j.devcel.2017.04.003. Dev Cell. 2017. PMID: 28486130 Free PMC article.
807 results