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A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic.
Shapira T, Monreal IA, Dion SP, Buchholz DW, Imbiakha B, Olmstead AD, Jager M, Désilets A, Gao G, Martins M, Vandal T, Thompson CAH, Chin A, Rees WD, Steiner T, Nabi IR, Marsault E, Sahler J, Diel DG, Van de Walle GR, August A, Whittaker GR, Boudreault PL, Leduc R, Aguilar HC, Jean F. Shapira T, et al. Among authors: sahler j. Nature. 2022 May;605(7909):340-348. doi: 10.1038/s41586-022-04661-w. Epub 2022 Mar 28. Nature. 2022. PMID: 35344983 Free PMC article.
Genetic Analysis of iNKT Cell Development and Function.
Sahler J, Anannya O, Limper C, Imbiakha B, Pierpont T, August A. Sahler J, et al. Methods Mol Biol. 2021;2388:1-12. doi: 10.1007/978-1-0716-1775-5_1. Methods Mol Biol. 2021. PMID: 34524657 Review.
Multivalent viral particles elicit safe and efficient immunoprotection against Nipah Hendra and Ebola viruses.
Ithinji DG, Buchholz DW, Ezzatpour S, Monreal IA, Cong Y, Sahler J, Bangar AS, Imbiakha B, Upadhye V, Liang J, Ma A, Bradel-Tretheway B, Kaza B, Yeo YY, Choi EJ, Johnston GP, Huzella L, Kollins E, Dixit S, Yu S, Postnikova E, Ortega V, August A, Holbrook MR, Aguilar HC. Ithinji DG, et al. Among authors: sahler j. NPJ Vaccines. 2022 Dec 17;7(1):166. doi: 10.1038/s41541-022-00588-5. NPJ Vaccines. 2022. PMID: 36528644 Free PMC article.
Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection.
Tang AT, Buchholz DW, Szigety KM, Imbiakha B, Gao S, Frankfurter M, Wang M, Yang J, Hewins P, Mericko-Ishizuka P, Leu NA, Sterling S, Monreal IA, Sahler J, August A, Zhu X, Jurado KA, Xu M, Morrisey EE, Millar SE, Aguilar HC, Kahn ML. Tang AT, et al. Among authors: sahler j. PLoS Biol. 2023 Feb 6;21(2):e3001989. doi: 10.1371/journal.pbio.3001989. eCollection 2023 Feb. PLoS Biol. 2023. PMID: 36745682 Free PMC article.
Effects of PFOS and cyclophosphamide exposure on immune homeostasis in mice.
Pierpont TM, Limper C, Elmore J, Redko A, Anannya O, Imbiakha B, Villanueva A, Anronikov S, Bondah N, Chang S, Sahler J, August A. Pierpont TM, et al. Among authors: sahler j. Immunobiology. 2023 May;228(3):152356. doi: 10.1016/j.imbio.2023.152356. Epub 2023 Feb 22. Immunobiology. 2023. PMID: 36857909 Free article.
Thermophobic Trehalose Glycopolymers as Smart C-Type Lectin Receptor Vaccine Adjuvants.
Hendricksen AT, Ezzatpour S, Pulukuri AJ, Ryan AT, Flanagan TJ, Frantz W, Buchholz DW, Ortega V, Monreal IA, Sahler JM, Nielsen AE, Aguilar HC, Mancini RJ. Hendricksen AT, et al. Among authors: sahler jm. Adv Healthc Mater. 2023 Jul;12(19):e2202918. doi: 10.1002/adhm.202202918. Epub 2023 Apr 25. Adv Healthc Mater. 2023. PMID: 37002787
Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure.
Polesskaya O, Cunningham LL, Francis SP, Luebke AE, Zhu X, Collins D, Vasilyeva ON, Sahler J, Desmet EA, Gelbard HA, Maggirwar SB, Walton JP, Frisina RD Jr, Dewhurst S. Polesskaya O, et al. Among authors: sahler j. Hear Res. 2010 Dec 1;270(1-2):21-7. doi: 10.1016/j.heares.2010.10.008. Epub 2010 Oct 27. Hear Res. 2010. PMID: 20971179 Free PMC article.
23 results