Sagare AP - Search Results

1

Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction.

Nation DA, Sweeney MD, Montagne A, Sagare AP, D'Orazio LM, Pachicano M, Sepehrband F, Nelson AR, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Chui HC, Law M, Toga AW, Zlokovic BV. Nation DA, et al. Among authors: sagare ap. Nat Med. 2019 Feb;25(2):270-276. doi: 10.1038/s41591-018-0297-y. Epub 2019 Jan 14. Nat Med. 2019. PMID: 30643288 Free PMC article.

2

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

Deane R, Wu Z, Sagare A, Davis J, Du Yan S, Hamm K, Xu F, Parisi M, LaRue B, Hu HW, Spijkers P, Guo H, Song X, Lenting PJ, Van Nostrand WE, Zlokovic BV. Deane R, et al. Neuron. 2004 Aug 5;43(3):333-44. doi: 10.1016/j.neuron.2004.07.017. Neuron. 2004. PMID: 15294142 Free article.

3

Method for measurement of the blood-brain barrier permeability in the perfused mouse brain: application to amyloid-beta peptide in wild type and Alzheimer's Tg2576 mice.

LaRue B, Hogg E, Sagare A, Jovanovic S, Maness L, Maurer C, Deane R, Zlokovic BV. LaRue B, et al. J Neurosci Methods. 2004 Sep 30;138(1-2):233-42. doi: 10.1016/j.jneumeth.2004.04.026. J Neurosci Methods. 2004. PMID: 15325132

4

Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease.

Wu Z, Guo H, Chow N, Sallstrom J, Bell RD, Deane R, Brooks AI, Kanagala S, Rubio A, Sagare A, Liu D, Li F, Armstrong D, Gasiewicz T, Zidovetzki R, Song X, Hofman F, Zlokovic BV. Wu Z, et al. Nat Med. 2005 Sep;11(9):959-65. doi: 10.1038/nm1287. Epub 2005 Aug 14. Nat Med. 2005. PMID: 16116430 Free article.

5

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.

Cirrito JR, Deane R, Fagan AM, Spinner ML, Parsadanian M, Finn MB, Jiang H, Prior JL, Sagare A, Bales KR, Paul SM, Zlokovic BV, Piwnica-Worms D, Holtzman DM. Cirrito JR, et al. J Clin Invest. 2005 Nov;115(11):3285-90. doi: 10.1172/JCI25247. Epub 2005 Oct 20. J Clin Invest. 2005. PMID: 16239972 Free PMC article.

6

IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor.

Deane R, Sagare A, Hamm K, Parisi M, LaRue B, Guo H, Wu Z, Holtzman DM, Zlokovic BV. Deane R, et al. J Neurosci. 2005 Dec 14;25(50):11495-503. doi: 10.1523/JNEUROSCI.3697-05.2005. J Neurosci. 2005. PMID: 16354907 Free PMC article.

7

Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system.

Bell RD, Sagare AP, Friedman AE, Bedi GS, Holtzman DM, Deane R, Zlokovic BV. Bell RD, et al. Among authors: sagare ap. J Cereb Blood Flow Metab. 2007 May;27(5):909-18. doi: 10.1038/sj.jcbfm.9600419. Epub 2006 Nov 1. J Cereb Blood Flow Metab. 2007. PMID: 17077814 Free PMC article.

8

Clearance of amyloid-beta by circulating lipoprotein receptors.

Sagare A, Deane R, Bell RD, Johnson B, Hamm K, Pendu R, Marky A, Lenting PJ, Wu Z, Zarcone T, Goate A, Mayo K, Perlmutter D, Coma M, Zhong Z, Zlokovic BV. Sagare A, et al. Nat Med. 2007 Sep;13(9):1029-31. doi: 10.1038/nm1635. Epub 2007 Aug 12. Nat Med. 2007. PMID: 17694066 Free PMC article.

9

ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration.

Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O'Banion MK, Stojanovic K, Sagare A, Boillee S, Cleveland DW, Zlokovic BV. Zhong Z, et al. Nat Neurosci. 2008 Apr;11(4):420-2. doi: 10.1038/nn2073. Epub 2008 Mar 16. Nat Neurosci. 2008. PMID: 18344992 Free PMC article.

10

The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease.

Deane R, Sagare A, Zlokovic BV. Deane R, et al. Curr Pharm Des. 2008;14(16):1601-5. doi: 10.2174/138161208784705487. Curr Pharm Des. 2008. PMID: 18673201 Free PMC article. Review.

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