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Renalase prevents AKI independent of amine oxidase activity.
Wang L, Velazquez H, Moeckel G, Chang J, Ham A, Lee HT, Safirstein R, Desir GV. Wang L, et al. Among authors: safirstein r. J Am Soc Nephrol. 2014 Jun;25(6):1226-35. doi: 10.1681/ASN.2013060665. Epub 2014 Feb 7. J Am Soc Nephrol. 2014. PMID: 24511138 Free PMC article.
Identification of a receptor for extracellular renalase.
Wang L, Velazquez H, Chang J, Safirstein R, Desir GV. Wang L, et al. Among authors: safirstein r. PLoS One. 2015 Apr 23;10(4):e0122932. doi: 10.1371/journal.pone.0122932. eCollection 2015. PLoS One. 2015. PMID: 25906147 Free PMC article.
Extracellular renalase protects cells and organs by outside-in signalling.
Wang Y, Safirstein R, Velazquez H, Guo XJ, Hollander L, Chang J, Chen TM, Mu JJ, Desir GV. Wang Y, et al. Among authors: safirstein r. J Cell Mol Med. 2017 Jul;21(7):1260-1265. doi: 10.1111/jcmm.13062. Epub 2017 Feb 26. J Cell Mol Med. 2017. PMID: 28238213 Free PMC article. Review.
Inhibition of renalase drives tumour rejection by promoting T cell activation.
Guo X, Jessel S, Qu R, Kluger Y, Chen TM, Hollander L, Safirstein R, Nelson B, Cha C, Bosenberg M, Jilaveanu LB, Rimm D, Rothlin CV, Kluger HM, Desir GV. Guo X, et al. Among authors: safirstein r. Eur J Cancer. 2022 Apr;165:81-96. doi: 10.1016/j.ejca.2022.01.002. Epub 2022 Feb 24. Eur J Cancer. 2022. PMID: 35219026 Free PMC article.
Association of renalase with clinical outcomes in hospitalized patients with COVID-19.
Safdar B, Wang M, Guo X, Cha C, Chun HJ, Deng Y, Dziura J, El-Khoury JM, Gorelick F, Ko AI, Lee AI, Safirstein R, Simonov M, Zhou B, Desir GV. Safdar B, et al. Among authors: safirstein r. PLoS One. 2022 Mar 8;17(3):e0264178. doi: 10.1371/journal.pone.0264178. eCollection 2022. PLoS One. 2022. PMID: 35259186 Free PMC article.
97 results