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Reduced phosphoinositide 3-kinase (p110alpha) activation increases the susceptibility to atrial fibrillation.
Pretorius L, Du XJ, Woodcock EA, Kiriazis H, Lin RC, Marasco S, Medcalf RL, Ming Z, Head GA, Tan JW, Cemerlang N, Sadoshima J, Shioi T, Izumo S, Lukoshkova EV, Dart AM, Jennings GL, McMullen JR. Pretorius L, et al. Among authors: sadoshima j. Am J Pathol. 2009 Sep;175(3):998-1009. doi: 10.2353/ajpath.2009.090126. Epub 2009 Aug 13. Am J Pathol. 2009. PMID: 19679877 Free PMC article.
The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice.
Sapra G, Tham YK, Cemerlang N, Matsumoto A, Kiriazis H, Bernardo BC, Henstridge DC, Ooi JY, Pretorius L, Boey EJ, Lim L, Sadoshima J, Meikle PJ, Mellet NA, Woodcock EA, Marasco S, Ueyama T, Du XJ, Febbraio MA, McMullen JR. Sapra G, et al. Among authors: sadoshima j. Nat Commun. 2014 Dec 9;5:5705. doi: 10.1038/ncomms6705. Nat Commun. 2014. PMID: 25489988 Free article.
Mitochondrial autophagy in cardiomyopathy.
Tong M, Sadoshima J. Tong M, et al. Among authors: sadoshima j. Curr Opin Genet Dev. 2016 Jun;38:8-15. doi: 10.1016/j.gde.2016.02.006. Epub 2016 Mar 19. Curr Opin Genet Dev. 2016. PMID: 27003723 Free PMC article. Review.
NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in the Heart.
Matsuda T, Zhai P, Sciarretta S, Zhang Y, Jeong JI, Ikeda S, Park J, Hsu CP, Tian B, Pan D, Sadoshima J, Del Re DP. Matsuda T, et al. Among authors: sadoshima j. Circ Res. 2016 Aug 19;119(5):596-606. doi: 10.1161/CIRCRESAHA.116.308586. Epub 2016 Jul 11. Circ Res. 2016. PMID: 27402866 Free PMC article.
Distinct lipidomic profiles in models of physiological and pathological cardiac remodeling, and potential therapeutic strategies.
Tham YK, Huynh K, Mellett NA, Henstridge DC, Kiriazis H, Ooi JYY, Matsumoto A, Patterson NL, Sadoshima J, Meikle PJ, McMullen JR. Tham YK, et al. Among authors: sadoshima j. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Mar;1863(3):219-234. doi: 10.1016/j.bbalip.2017.12.003. Epub 2017 Dec 6. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 29217479
390 results