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Road Map for Development of Stem Cell-Based Alternative Test Methods.
Sachinidis A, Albrecht W, Nell P, Cherianidou A, Hewitt NJ, Edlund K, Hengstler JG. Sachinidis A, et al. Trends Mol Med. 2019 Jun;25(6):470-481. doi: 10.1016/j.molmed.2019.04.003. Epub 2019 May 23. Trends Mol Med. 2019. PMID: 31130451 Review.
Embryonic stem cells: a promising tool for cell replacement therapy.
Doss MX, Koehler CI, Gissel C, Hescheler J, Sachinidis A. Doss MX, et al. Among authors: sachinidis a. J Cell Mol Med. 2004 Oct-Dec;8(4):465-73. doi: 10.1111/j.1582-4934.2004.tb00471.x. J Cell Mol Med. 2004. PMID: 15601575 Free PMC article. Review.
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.
Krug AK, Kolde R, Gaspar JA, Rempel E, Balmer NV, Meganathan K, Vojnits K, Baquié M, Waldmann T, Ensenat-Waser R, Jagtap S, Evans RM, Julien S, Peterson H, Zagoura D, Kadereit S, Gerhard D, Sotiriadou I, Heke M, Natarajan K, Henry M, Winkler J, Marchan R, Stoppini L, Bosgra S, Westerhout J, Verwei M, Vilo J, Kortenkamp A, Hescheler J, Hothorn L, Bremer S, van Thriel C, Krause KH, Hengstler JG, Rahnenführer J, Leist M, Sachinidis A. Krug AK, et al. Among authors: sachinidis a. Arch Toxicol. 2013 Jan;87(1):123-43. doi: 10.1007/s00204-012-0967-3. Epub 2012 Nov 21. Arch Toxicol. 2013. PMID: 23179753 Free PMC article.
Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes.
Schug M, Stöber R, Heise T, Mielke H, Gundert-Remy U, Godoy P, Reif R, Blaszkewicz M, Ellinger-Ziegelbauer H, Ahr HJ, Selinski S, Günther G, Marchan R, Blaszkewicz M, Sachinidis A, Nüssler A, Oberemm A, Hengstler JG. Schug M, et al. Among authors: sachinidis a. Arch Toxicol. 2013 Feb;87(2):337-45. doi: 10.1007/s00204-012-0999-8. Epub 2012 Dec 29. Arch Toxicol. 2013. PMID: 23274394
Test systems of developmental toxicity: state-of-the art and future perspectives.
Leist M, Ringwald A, Kolde R, Bremer S, van Thriel C, Krause KH, Rahnenführer J, Sachinidis A, Hescheler J, Hengstler JG. Leist M, et al. Among authors: sachinidis a. Arch Toxicol. 2013 Dec;87(12):2037-42. doi: 10.1007/s00204-013-1154-x. Arch Toxicol. 2013. PMID: 24190503 No abstract available.
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery.
Zimmer B, Pallocca G, Dreser N, Foerster S, Waldmann T, Westerhout J, Julien S, Krause KH, van Thriel C, Hengstler JG, Sachinidis A, Bosgra S, Leist M. Zimmer B, et al. Among authors: sachinidis a. Arch Toxicol. 2014 May;88(5):1109-26. doi: 10.1007/s00204-014-1231-9. Epub 2014 Apr 2. Arch Toxicol. 2014. PMID: 24691702 Free PMC article.
The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity.
Campos G, Schmidt-Heck W, Ghallab A, Rochlitz K, Pütter L, Medinas DB, Hetz C, Widera A, Cadenas C, Begher-Tibbe B, Reif R, Günther G, Sachinidis A, Hengstler JG, Godoy P. Campos G, et al. Among authors: sachinidis a. Arch Toxicol. 2014 Jun;88(6):1267-80. doi: 10.1007/s00204-014-1240-8. Epub 2014 Apr 20. Arch Toxicol. 2014. PMID: 24748426
335 results