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Epigenetic variations are more substantial than genetic variations in rapid adaptation of oyster to Pacific oyster mortality syndrome.
Gawra J, Valdivieso A, Roux F, Laporte M, de Lorgeril J, Gueguen Y, Saccas M, Escoubas JM, Montagnani C, Destoumieux-Garzόn D, Lagarde F, Leroy MA, Haffner P, Petton B, Cosseau C, Morga B, Dégremont L, Mitta G, Grunau C, Vidal-Dupiol J. Gawra J, et al. Among authors: saccas m. Sci Adv. 2023 Sep 8;9(36):eadh8990. doi: 10.1126/sciadv.adh8990. Epub 2023 Sep 8. Sci Adv. 2023. PMID: 37683000 Free PMC article.
TL-532, a novel specific Toll-like receptor 3 agonist rationally designed for targeting cancers: discovery process and biological characterization.
Thierry S, Maadadi S, Berton A, Dimier L, Perret C, Vey N, Ourfali S, Saccas M, Caron S, Boucard-Jourdin M, Colombel M, Werle B, Bonnin M. Thierry S, et al. Among authors: saccas m. Microb Cell. 2023 Apr 19;10(6):117-132. doi: 10.15698/mic2023.06.797. eCollection 2023 Jun 5. Microb Cell. 2023. PMID: 37275475 Free PMC article.
DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma.
Taffoni C, Marines J, Chamma H, Guha S, Saccas M, Bouzid A, Valadao AC, Maghe C, Jardine J, Park MK, Polak K, De Martino M, Vanpouille-Box C, Del Rio M, Gongora C, Gavard J, Bidère N, Song MS, Pineau D, Hugnot JP, Kissa K, Fontenille L, Blanchet FP, Vila IK, Laguette N. Taffoni C, et al. Among authors: saccas m. EMBO J. 2023 Apr 3;42(7):e111961. doi: 10.15252/embj.2022111961. Epub 2022 Dec 27. EMBO J. 2023. PMID: 36574362 Free PMC article.
STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses.
Vila IK, Chamma H, Steer A, Saccas M, Taffoni C, Turtoi E, Reinert LS, Hussain S, Marines J, Jin L, Bonnefont X, Hubert M, Schwartz O, Paludan SR, Van Simaeys G, Doumont G, Sobhian B, Vlachakis D, Turtoi A, Laguette N. Vila IK, et al. Among authors: saccas m. Cell Metab. 2022 Jan 4;34(1):125-139.e8. doi: 10.1016/j.cmet.2021.12.007. Cell Metab. 2022. PMID: 34986331 Free PMC article.