Saber S - Search Results

1

Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis.

Youssef ME, Abd El-Fattah EE, Abdelhamid AM, Eissa H, El-Ahwany E, Amin NA, Hetta HF, Mahmoud MH, Batiha GE, Gobba N, Ahmed Gaafar AG, Saber S. Youssef ME, et al. Among authors: saber s. Front Pharmacol. 2021 Aug 16;12:719984. doi: 10.3389/fphar.2021.719984. eCollection 2021. Front Pharmacol. 2021. PMID: 34489707 Free PMC article.

2

Renin-angiotensin system inhibition ameliorates CCl₄-induced liver fibrosis in mice through the inactivation of nuclear transcription factor kappa B.

Saber S, Mahmoud AAA, Helal NS, El-Ahwany E, Abdelghany RH. Saber S, et al. Can J Physiol Pharmacol. 2018 Jun;96(6):569-576. doi: 10.1139/cjpp-2017-0728. Epub 2018 Feb 9. Can J Physiol Pharmacol. 2018. PMID: 29425464

3

Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B.

Saber S, Mahmoud AAA, Goda R, Helal NS, El-Ahwany E, Abdelghany RH. Saber S, et al. Toxicol Lett. 2018 Oct 1;295:32-40. doi: 10.1016/j.toxlet.2018.05.036. Epub 2018 May 31. Toxicol Lett. 2018. PMID: 29859236

4

Liver Protective Effects of Renin-Angiotensin System Inhibition Have No Survival Benefits in Hepatocellular Carcinoma Induced By Repetitive Administration of Diethylnitrosamine in Mice.

Saber S, Mahmoud A, Helal N, El-Ahwany E, Abdelghany R. Saber S, et al. Open Access Maced J Med Sci. 2018 Jun 6;6(6):955-960. doi: 10.3889/oamjms.2018.167. eCollection 2018 Jun 20. Open Access Maced J Med Sci. 2018. PMID: 29983784 Free PMC article.

5

Olmesartan ameliorates chemically-induced ulcerative colitis in rats via modulating NFκB and Nrf-2/HO-1 signaling crosstalk.

Saber S, Khalil RM, Abdo WS, Nassif D, El-Ahwany E. Saber S, et al. Toxicol Appl Pharmacol. 2019 Feb 1;364:120-132. doi: 10.1016/j.taap.2018.12.020. Epub 2018 Dec 27. Toxicol Appl Pharmacol. 2019. PMID: 30594690

6

Novel complementary antitumour effects of celastrol and metformin by targeting IκBκB, apoptosis and NLRP3 inflammasome activation in diethylnitrosamine-induced murine hepatocarcinogenesis.

Saber S, Ghanim AMH, El-Ahwany E, El-Kader EMA. Saber S, et al. Cancer Chemother Pharmacol. 2020 Feb;85(2):331-343. doi: 10.1007/s00280-020-04033-z. Epub 2020 Jan 27. Cancer Chemother Pharmacol. 2020. PMID: 31989218

7

Celastrol augments sensitivity of NLRP3 to CP-456773 by modulating HSP-90 and inducing autophagy in dextran sodium sulphate-induced colitis in rats.

Saber S, Abd El-Kader EM, Sharaf H, El-Shamy R, El-Saeed B, Mostafa A, Ezzat D, Shata A. Saber S, et al. Toxicol Appl Pharmacol. 2020 Aug 1;400:115075. doi: 10.1016/j.taap.2020.115075. Epub 2020 May 26. Toxicol Appl Pharmacol. 2020. PMID: 32470352

8

Vildagliptin, a DPP-4 inhibitor, attenuates carbon tetrachloride-induced liver fibrosis by targeting ERK1/2, p38α, and NF-κB signaling.

Khalil R, Shata A, Abd El-Kader EM, Sharaf H, Abdo WS, Amin NA, Saber S. Khalil R, et al. Among authors: saber s. Toxicol Appl Pharmacol. 2020 Nov 15;407:115246. doi: 10.1016/j.taap.2020.115246. Epub 2020 Sep 19. Toxicol Appl Pharmacol. 2020. PMID: 32956689

9

BBG enhances OLT1177-induced NLRP3 inflammasome inactivation by targeting P2X7R/NLRP3 and MyD88/NF-κB signaling in DSS-induced colitis in rats.

Saber S, Youssef ME, Sharaf H, Amin NA, El-Shedody R, Aboutouk FH, El-Galeel YA, El-Hefnawy A, Shabaka D, Khalifa A, Saleh RA, Osama D, El-Zoghby G, Gobba NA. Saber S, et al. Life Sci. 2021 Apr 1;270:119123. doi: 10.1016/j.lfs.2021.119123. Epub 2021 Feb 3. Life Sci. 2021. PMID: 33548287

10

A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the TXNIP/NLRP3 Interaction and Influencing Gut Microbiome Composition.

Saber S, Abd El-Fattah EE, Yahya G, Gobba NA, Maghmomeh AO, Khodir AE, Mourad AAE, Saad AS, Mohammed HG, Nouh NA, Shata A, Amin NA, Abou El-Rous M, Girgis S, El-Ahwany E, Khalaf EM, El-Kott AF, El-Baz AM. Saber S, et al. Pharmaceuticals (Basel). 2021 Apr 8;14(4):341. doi: 10.3390/ph14040341. Pharmaceuticals (Basel). 2021. PMID: 33917884 Free PMC article.

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