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Fragmentation of Escherichia coli mRNA by MazF and MqsR.
Mets T, Kasvandik S, Saarma M, Maiväli Ü, Tenson T, Kaldalu N. Mets T, et al. Among authors: saarma m. Biochimie. 2019 Jan;156:79-91. doi: 10.1016/j.biochi.2018.10.004. Epub 2018 Oct 10. Biochimie. 2019. PMID: 30315853
CDNF and ER stress: Pharmacology and therapeutic possibilities.
Lõhelaid H, Saarma M, Airavaara M. Lõhelaid H, et al. Among authors: saarma m. Pharmacol Ther. 2024 Feb;254:108594. doi: 10.1016/j.pharmthera.2024.108594. Epub 2024 Jan 28. Pharmacol Ther. 2024. PMID: 38290651 Free article. Review.
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB.
Moliner R, Girych M, Brunello CA, Kovaleva V, Biojone C, Enkavi G, Antenucci L, Kot EF, Goncharuk SA, Kaurinkoski K, Kuutti M, Fred SM, Elsilä LV, Sakson S, Cannarozzo C, Diniz CRAF, Seiffert N, Rubiolo A, Haapaniemi H, Meshi E, Nagaeva E, Öhman T, Róg T, Kankuri E, Vilar M, Varjosalo M, Korpi ER, Permi P, Mineev KS, Saarma M, Vattulainen I, Casarotto PC, Castrén E. Moliner R, et al. Among authors: saarma m. Nat Neurosci. 2023 Jun;26(6):1032-1041. doi: 10.1038/s41593-023-01316-5. Epub 2023 Jun 5. Nat Neurosci. 2023. PMID: 37280397 Free PMC article.
Intraputamenal Cerebral Dopamine Neurotrophic Factor in Parkinson's Disease: A Randomized, Double-Blind, Multicenter Phase 1 Trial.
Huttunen HJ, Booms S, Sjögren M, Kerstens V, Johansson J, Holmnäs R, Koskinen J, Kulesskaya N, Fazio P, Woolley M, Brady A, Williams J, Johnson D, Dailami N, Gray W, Levo R, Saarma M, Halldin C, Marjamaa J, Resendiz-Nieves J, Grubor I, Lind G, Eerola-Rautio J, Mertsalmi T, Andréasson M, Paul G, Rinne J, Kivisaari R, Bjartmarz H, Almqvist P, Varrone A, Scheperjans F, Widner H, Svenningsson P. Huttunen HJ, et al. Among authors: saarma m. Mov Disord. 2023 Jul;38(7):1209-1222. doi: 10.1002/mds.29426. Epub 2023 May 22. Mov Disord. 2023. PMID: 37212361 Clinical Trial.
CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress.
De Lorenzo F, Lüningschrör P, Nam J, Beckett L, Pilotto F, Galli E, Lindholm P, Rüdt von Collenberg C, Mungwa ST, Jablonka S, Kauder J, Thau-Habermann N, Petri S, Lindholm D, Saxena S, Sendtner M, Saarma M, Voutilainen MH. De Lorenzo F, et al. Among authors: saarma m. Brain. 2023 Sep 1;146(9):3783-3799. doi: 10.1093/brain/awad087. Brain. 2023. PMID: 36928391 Free PMC article.
Augmenting hematoma-scavenging capacity of innate immune cells by CDNF reduces brain injury and promotes functional recovery after intracerebral hemorrhage.
Tseng KY, Stratoulias V, Hu WF, Wu JS, Wang V, Chen YH, Seelbach A, Huttunen HJ, Kulesskaya N, Pang CY, Chou JL, Lindahl M, Saarma M, Huang LC, Airavaara M, Liew HK. Tseng KY, et al. Among authors: saarma m. Cell Death Dis. 2023 Feb 15;14(2):128. doi: 10.1038/s41419-022-05520-2. Cell Death Dis. 2023. PMID: 36792604 Free PMC article.
298 results