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Activation of endogenous retroviruses during brain development causes an inflammatory response.
Jönsson ME, Garza R, Sharma Y, Petri R, Södersten E, Johansson JG, Johansson PA, Atacho DA, Pircs K, Madsen S, Yudovich D, Ramakrishnan R, Holmberg J, Larsson J, Jern P, Jakobsson J. Jönsson ME, et al. Among authors: sodersten e. EMBO J. 2021 May 3;40(9):e106423. doi: 10.15252/embj.2020106423. Epub 2021 Mar 1. EMBO J. 2021. PMID: 33644903 Free PMC article.
PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons.
Toskas K, Yaghmaeian-Salmani B, Skiteva O, Paslawski W, Gillberg L, Skara V, Antoniou I, Södersten E, Svenningsson P, Chergui K, Ringnér M, Perlmann T, Holmberg J. Toskas K, et al. Among authors: sodersten e. Sci Adv. 2022 Aug 26;8(34):eabo1543. doi: 10.1126/sciadv.abo1543. Epub 2022 Aug 26. Sci Adv. 2022. PMID: 36026451 Free PMC article.
Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression.
Westerlund I, Shi Y, Toskas K, Fell SM, Li S, Surova O, Södersten E, Kogner P, Nyman U, Schlisio S, Holmberg J. Westerlund I, et al. Among authors: sodersten e. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6137-E6146. doi: 10.1073/pnas.1700655114. Epub 2017 Jul 10. Proc Natl Acad Sci U S A. 2017. PMID: 28696319 Free PMC article.
Targeted intra-arterial transplantation of stem cells to the injured CNS is more effective than intravenous administration: engraftment is dependent on cell type and adhesion molecule expression.
Lundberg J, Södersten E, Sundström E, Le Blanc K, Andersson T, Hermanson O, Holmin S. Lundberg J, et al. Among authors: sodersten e. Cell Transplant. 2012;21(1):333-43. doi: 10.3727/096368911X576036. Epub 2011 Jun 7. Cell Transplant. 2012. PMID: 21669035 Free article.
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