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Page 1
Bioaccumulation of therapeutic drugs by human gut bacteria.
Klünemann M, Andrejev S, Blasche S, Mateus A, Phapale P, Devendran S, Vappiani J, Simon B, Scott TA, Kafkia E, Konstantinidis D, Zirngibl K, Mastrorilli E, Banzhaf M, Mackmull MT, Hövelmann F, Nesme L, Brochado AR, Maier L, Bock T, Periwal V, Kumar M, Kim Y, Tramontano M, Schultz C, Beck M, Hennig J, Zimmermann M, Sévin DC, Cabreiro F, Savitski MM, Bork P, Typas A, Patil KR. Klünemann M, et al. Among authors: sevin dc. Nature. 2021 Sep;597(7877):533-538. doi: 10.1038/s41586-021-03891-8. Epub 2021 Sep 8. Nature. 2021. PMID: 34497420 Free PMC article.
Yeast Creates a Niche for Symbiotic Lactic Acid Bacteria through Nitrogen Overflow.
Ponomarova O, Gabrielli N, Sévin DC, Mülleder M, Zirngibl K, Bulyha K, Andrejev S, Kafkia E, Typas A, Sauer U, Ralser M, Patil KR. Ponomarova O, et al. Among authors: sevin dc. Cell Syst. 2017 Oct 25;5(4):345-357.e6. doi: 10.1016/j.cels.2017.09.002. Epub 2017 Sep 27. Cell Syst. 2017. PMID: 28964698 Free PMC article.
Identifying drug targets in tissues and whole blood with thermal-shift profiling.
Perrin J, Werner T, Kurzawa N, Rutkowska A, Childs DD, Kalxdorf M, Poeckel D, Stonehouse E, Strohmer K, Heller B, Thomson DW, Krause J, Becher I, Eberl HC, Vappiani J, Sevin DC, Rau CE, Franken H, Huber W, Faelth-Savitski M, Savitski MM, Bantscheff M, Bergamini G. Perrin J, et al. Among authors: sevin dc. Nat Biotechnol. 2020 Mar;38(3):303-308. doi: 10.1038/s41587-019-0388-4. Epub 2020 Jan 20. Nat Biotechnol. 2020. PMID: 31959954
New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids.
Rodrigues D, de Souza T, Coyle L, Di Piazza M, Herpers B, Ferreira S, Zhang M, Vappiani J, Sévin DC, Gabor A, Lynch A, Chung SW, Saez-Rodriguez J, Jennen DGJ, Kleinjans JCS, de Kok TM. Rodrigues D, et al. Among authors: sevin dc. Arch Toxicol. 2021 Aug;95(8):2691-2718. doi: 10.1007/s00204-021-03092-2. Epub 2021 Jun 20. Arch Toxicol. 2021. PMID: 34151400 Free PMC article.
Metabolic memory underlying minimal residual disease in breast cancer.
Radic Shechter K, Kafkia E, Zirngibl K, Gawrzak S, Alladin A, Machado D, Lüchtenborg C, Sévin DC, Brügger B, Patil KR, Jechlinger M. Radic Shechter K, et al. Among authors: sevin dc. Mol Syst Biol. 2021 Oct;17(10):e10141. doi: 10.15252/msb.202010141. Mol Syst Biol. 2021. PMID: 34694069 Free PMC article.
Consistency across multi-omics layers in a drug-perturbed gut microbial community.
Wuyts S, Alves R, Zimmermann-Kogadeeva M, Nishijima S, Blasche S, Driessen M, Geyer PE, Hercog R, Kartal E, Maier L, Müller JB, Garcia Santamarina S, Schmidt TSB, Sevin DC, Telzerow A, Treit PV, Wenzel T, Typas A, Patil KR, Mann M, Kuhn M, Bork P. Wuyts S, et al. Among authors: sevin dc. Mol Syst Biol. 2023 Sep 12;19(9):e11525. doi: 10.15252/msb.202311525. Epub 2023 Jul 24. Mol Syst Biol. 2023. PMID: 37485738 Free PMC article.
27 results