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Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex.
Hernández-Ortega S, Sánchez-Botet A, Quandt E, Masip N, Gasa L, Verde G, Jiménez J, Levin RS, Rutaganira FU, Burlingame AL, Wolfgeher D, Ribeiro MPC, Kron SJ, Shokat KM, Clotet J. Hernández-Ortega S, et al. Among authors: sanchez botet a. Exp Mol Med. 2019 Apr 16;51(4):1-17. doi: 10.1038/s12276-019-0242-2. Exp Mol Med. 2019. PMID: 30992425 Free PMC article.
The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration.
Sánchez-Botet A, Gasa L, Quandt E, Hernández-Ortega S, Jiménez J, Mezquita P, Carrasco-García MÀ, Kron SJ, Vidal A, Villanueva A, Ribeiro MPC, Clotet J. Sánchez-Botet A, et al. Sci Rep. 2018 Aug 7;8(1):11797. doi: 10.1038/s41598-018-30307-x. Sci Rep. 2018. PMID: 30087414 Free PMC article.
CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation.
Quandt E, Masip N, Hernández-Ortega S, Sánchez-Botet A, Gasa L, Fernández-Elorduy A, Plutta S, Martínez-Láinez JM, Bru S, Munoz-Torres PM, Floor M, Villà-Freixa J, Morris MC, Vidal A, Villanueva A, Clotet J, Ribeiro MPC. Quandt E, et al. Among authors: sanchez botet a. Mol Oncol. 2023 Jul;17(7):1228-1245. doi: 10.1002/1878-0261.13438. Epub 2023 May 31. Mol Oncol. 2023. PMID: 37081792 Free PMC article.