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Page 1
mRNA 3'UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus.
Bergant V, Schnepf D, de Andrade Krätzig N, Hubel P, Urban C, Engleitner T, Dijkman R, Ryffel B, Steiger K, Knolle PA, Kochs G, Rad R, Staeheli P, Pichlmair A. Bergant V, et al. Among authors: ryffel b. Nat Commun. 2023 Aug 15;14(1):4906. doi: 10.1038/s41467-023-40469-6. Nat Commun. 2023. PMID: 37582777 Free PMC article.
The alternative cap-binding complex is required for antiviral defense in vivo.
Gebhardt A, Bergant V, Schnepf D, Moser M, Meiler A, Togbe D, Mackowiak C, Reinert LS, Paludan SR, Ryffel B, Stukalov A, Staeheli P, Pichlmair A. Gebhardt A, et al. Among authors: ryffel b. PLoS Pathog. 2019 Dec 19;15(12):e1008155. doi: 10.1371/journal.ppat.1008155. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31856218 Free PMC article.
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.
Holze C, Michaudel C, Mackowiak C, Haas DA, Benda C, Hubel P, Pennemann FL, Schnepf D, Wettmarshausen J, Braun M, Leung DW, Amarasinghe GK, Perocchi F, Staeheli P, Ryffel B, Pichlmair A. Holze C, et al. Among authors: ryffel b. Nat Immunol. 2018 Feb;19(2):130-140. doi: 10.1038/s41590-017-0013-y. Epub 2017 Dec 18. Nat Immunol. 2018. PMID: 29255269 Free PMC article.
Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection.
Hernández PP, Mahlakoiv T, Yang I, Schwierzeck V, Nguyen N, Guendel F, Gronke K, Ryffel B, Hoelscher C, Dumoutier L, Renauld JC, Suerbaum S, Staeheli P, Diefenbach A. Hernández PP, et al. Among authors: ryffel b. Nat Immunol. 2015 Jul;16(7):698-707. doi: 10.1038/ni.3180. Epub 2015 May 25. Nat Immunol. 2015. PMID: 26006013 Free PMC article.
STING-dependent sensing of self-DNA drives silica-induced lung inflammation.
Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, Mollet L, Le Bert M, Lambers C, Geleff S, Roth M, Fauconnier L, Sedda D, Carvalho C, Perche O, Laurenceau D, Ryffel B, Apetoh L, Kiziltunc A, Uslu H, Albez FS, Akgun M, Togbe D, Quesniaux VFJ. Benmerzoug S, et al. Among authors: ryffel b. Nat Commun. 2018 Dec 6;9(1):5226. doi: 10.1038/s41467-018-07425-1. Nat Commun. 2018. PMID: 30523277 Free PMC article.
A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy.
Douguet L, Janho Dit Hreich S, Benzaquen J, Seguin L, Juhel T, Dezitter X, Duranton C, Ryffel B, Kanellopoulos J, Delarasse C, Renault N, Furman C, Homerin G, Féral C, Cherfils-Vicini J, Millet R, Adriouch S, Ghinet A, Hofman P, Vouret-Craviari V. Douguet L, et al. Among authors: ryffel b. Nat Commun. 2021 Jan 28;12(1):653. doi: 10.1038/s41467-021-20912-2. Nat Commun. 2021. PMID: 33510147 Free PMC article.
Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens.
Normand S, Waldschmitt N, Neerincx A, Martinez-Torres RJ, Chauvin C, Couturier-Maillard A, Boulard O, Cobret L, Awad F, Huot L, Ribeiro-Ribeiro A, Lautz K, Ruez R, Delacre M, Bondu C, Guilliams M, Scott C, Segal A, Amselem S, Hot D, Karabina S, Bohn E, Ryffel B, Poulin LF, Kufer TA, Chamaillard M. Normand S, et al. Among authors: ryffel b. Nat Commun. 2018 Dec 17;9(1):5338. doi: 10.1038/s41467-018-07750-5. Nat Commun. 2018. PMID: 30559449 Free PMC article.
Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses.
Uyanik B, Goloudina AR, Akbarali A, Grigorash BB, Petukhov AV, Singhal S, Eruslanov E, Chaloyard J, Lagorgette L, Hadi T, Baidyuk EV, Sakai H, Tessarollo L, Ryffel B, Mazur SJ, Lirussi F, Garrido C, Appella E, Demidov ON. Uyanik B, et al. Among authors: ryffel b. Nat Commun. 2021 Jun 15;12(1):3622. doi: 10.1038/s41467-021-23330-6. Nat Commun. 2021. PMID: 34131120 Free PMC article.
Nitric oxide enhances Th9 cell differentiation and airway inflammation.
Niedbala W, Besnard AG, Nascimento DC, Donate PB, Sonego F, Yip E, Guabiraba R, Chang HD, Fukada SY, Salmond RJ, Schmitt E, Bopp T, Ryffel B, Liew FY. Niedbala W, et al. Among authors: ryffel b. Nat Commun. 2014 Aug 7;5:4575. doi: 10.1038/ncomms5575. Nat Commun. 2014. PMID: 25099390 Free PMC article.
Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages.
Paget C, Ivanov S, Fontaine J, Renneson J, Blanc F, Pichavant M, Dumoutier L, Ryffel B, Renauld JC, Gosset P, Gosset P, Si-Tahar M, Faveeuw C, Trottein F. Paget C, et al. Among authors: ryffel b. J Biol Chem. 2012 Mar 16;287(12):8816-29. doi: 10.1074/jbc.M111.304758. Epub 2012 Jan 31. J Biol Chem. 2012. PMID: 22294696 Free PMC article.
547 results