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Page 1
Effect of experimental hookworm infection on insulin resistance in people at risk of type 2 diabetes.
Pierce DR, McDonald M, Merone L, Becker L, Thompson F, Lewis C, Ryan RYM, Hii SF, Zendejas-Heredia PA, Traub RJ, Field MA, Rahman T, Croese J, Loukas A, McDermott R, Giacomin PR. Pierce DR, et al. Among authors: ryan rym. Nat Commun. 2023 Jul 26;14(1):4503. doi: 10.1038/s41467-023-40263-4. Nat Commun. 2023. PMID: 37495576 Free PMC article. Clinical Trial.
Peptides derived from hookworm anti-inflammatory proteins suppress inducible colitis in mice and inflammatory cytokine production by human cells.
Cobos C, Bansal PS, Wilson DT, Jones L, Zhao G, Field MA, Eichenberger RM, Pickering DA, Ryan RYM, Ratnatunga CN, Miles JJ, Ruscher R, Giacomin PR, Navarro S, Loukas A, Daly NL. Cobos C, et al. Among authors: ryan rym. Front Med (Lausanne). 2022 Sep 9;9:934852. doi: 10.3389/fmed.2022.934852. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36186812 Free PMC article.
Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes.
Wangchuk P, Shepherd C, Constantinoiu C, Ryan RYM, Kouremenos KA, Becker L, Jones L, Buitrago G, Giacomin P, Wilson D, Daly N, McConville MJ, Miles JJ, Loukas A. Wangchuk P, et al. Among authors: ryan rym. Infect Immun. 2019 Mar 25;87(4):e00851-18. doi: 10.1128/IAI.00851-18. Print 2019 Apr. Infect Immun. 2019. PMID: 30670556 Free PMC article.
Novel antiinflammatory biologics shaped by parasite-host coevolution.
Ryan SM, Ruscher R, Johnston WA, Pickering DA, Kennedy MW, Smith BO, Jones L, Buitrago G, Field MA, Esterman AJ, McHugh CP, Browne DJ, Cooper MM, Ryan RYM, Doolan DL, Engwerda CR, Miles K, Mitreva M, Croese J, Rahman T, Alexandrov K, Giacomin PR, Loukas A. Ryan SM, et al. Among authors: ryan rym. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2202795119. doi: 10.1073/pnas.2202795119. Epub 2022 Aug 29. Proc Natl Acad Sci U S A. 2022. PMID: 36037362 Free PMC article.
Synthetic hookworm-derived peptides are potent modulators of primary human immune cell function that protect against experimental colitis in vivo.
Smallwood TB, Navarro S, Cristofori-Armstrong B, Watkins TS, Tungatt K, Ryan RYM, Haigh OL, Lutzky VP, Mulvenna JP, Rosengren KJ, Loukas A, Miles JJ, Clark RJ. Smallwood TB, et al. Among authors: ryan rym. J Biol Chem. 2021 Jul;297(1):100834. doi: 10.1016/j.jbc.2021.100834. Epub 2021 May 27. J Biol Chem. 2021. PMID: 34051231 Free PMC article.
Immunological Responses to Envenomation.
Ryan RYM, Seymour J, Loukas A, Lopez JA, Ikonomopoulou MP, Miles JJ. Ryan RYM, et al. Front Immunol. 2021 May 10;12:661082. doi: 10.3389/fimmu.2021.661082. eCollection 2021. Front Immunol. 2021. PMID: 34040609 Free PMC article. Review.
Antibody response to common human viruses is shaped by genetic factors.
Hayward TA, Zhu G, Warrington NM, Wong Y, Ryan RYM, Murray AM, Haigh O, Martin NG, Miles JJ, Evans DM. Hayward TA, et al. Among authors: ryan rym. J Allergy Clin Immunol. 2019 Apr;143(4):1640-1643. doi: 10.1016/j.jaci.2018.11.039. Epub 2018 Dec 20. J Allergy Clin Immunol. 2019. PMID: 30578878 No abstract available.