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mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux.
Beaumatin F, O'Prey J, Barthet VJA, Zunino B, Parvy JP, Bachmann AM, O'Prey M, Kania E, Gonzalez PS, Macintosh R, Lao LY, Nixon C, Lopez J, Long JS, Tait SWG, Ryan KM. Beaumatin F, et al. Among authors: ryan km. Mol Cell. 2019 Oct 3;76(1):163-176.e8. doi: 10.1016/j.molcel.2019.07.021. Epub 2019 Sep 3. Mol Cell. 2019. PMID: 31492633 Free PMC article.
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.
Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, Gasco M, Garrone O, Crook T, Ryan KM. Crighton D, et al. Among authors: ryan km. Cell. 2006 Jul 14;126(1):121-34. doi: 10.1016/j.cell.2006.05.034. Cell. 2006. PMID: 16839881 Free article.
DRAM links autophagy to p53 and programmed cell death.
Crighton D, Wilkinson S, Ryan KM. Crighton D, et al. Among authors: ryan km. Autophagy. 2007 Jan-Feb;3(1):72-4. doi: 10.4161/auto.3438. Epub 2007 Jan 28. Autophagy. 2007. PMID: 17102582 Review.
322 results