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Citrullinated and malondialdehyde-acetaldehyde modified fibrinogen activates macrophages and promotes an aggressive synovial fibroblast phenotype in patients with rheumatoid arthritis.
Aripova N, Duryee MJ, England BR, Hunter CD, Mordeson JE, Ryan EM, Daubach EC, Romberger DJ, Thiele GM, Mikuls TR. Aripova N, et al. Among authors: ryan em. Front Immunol. 2023 Aug 16;14:1203548. doi: 10.3389/fimmu.2023.1203548. eCollection 2023. Front Immunol. 2023. PMID: 37654483 Free PMC article.
NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease.
Ryan EM, Sadiku P, Coelho P, Watts ER, Zhang A, Howden AJM, Sanchez-Garcia MA, Bewley M, Cole J, McHugh BJ, Vermaelen W, Ghesquiere B, Carmeliet P, Rodriguez Blanco G, Von Kriegsheim A, Sanchez Y, Rumsey W, Callahan JF, Cooper G, Parkinson N, Baillie K, Cantrell DA, McCafferty J, Choudhury G, Singh D, Dockrell DH, Whyte MKB, Walmsley SR. Ryan EM, et al. Am J Respir Crit Care Med. 2023 Apr 15;207(8):998-1011. doi: 10.1164/rccm.202203-0482OC. Am J Respir Crit Care Med. 2023. PMID: 36724365 Free PMC article.
Reply by Authors.
Ní Néill E, Richards HL, Hennessey D, Ryan EM, Fortune DG. Ní Néill E, et al. Among authors: ryan em. J Urol. 2023 Jan;209(1):70. doi: 10.1097/JU.0000000000003032.02. Epub 2023 Jan 1. J Urol. 2023. PMID: 36484443 No abstract available.
Peptidyl arginine deiminase expression and macrophage polarization following stimulation with citrullinated and malondialdehyde-acetaldehyde modified fibrinogen.
Aripova N, Duryee MJ, Hunter CD, Ryan EM, Daubach EC, Jones SQ, Bierman MM, Ragland AS, Mitra A, England BR, Romberger DJ, Thiele GM, Mikuls TR. Aripova N, et al. Among authors: ryan em. Int Immunopharmacol. 2022 Sep;110:109010. doi: 10.1016/j.intimp.2022.109010. Epub 2022 Jul 1. Int Immunopharmacol. 2022. PMID: 35785731
Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis.
Sadiku P, Willson JA, Ryan EM, Sammut D, Coelho P, Watts ER, Grecian R, Young JM, Bewley M, Arienti S, Mirchandani AS, Sanchez Garcia MA, Morrison T, Zhang A, Reyes L, Griessler T, Jheeta P, Paterson GG, Graham CJ, Thomson JP, Baillie K, Thompson AAR, Morgan JM, Acosta-Sanchez A, Dardé VM, Duran J, Guinovart JJ, Rodriguez-Blanco G, Von Kriegsheim A, Meehan RR, Mazzone M, Dockrell DH, Ghesquiere B, Carmeliet P, Whyte MKB, Walmsley SR. Sadiku P, et al. Among authors: ryan em. Cell Metab. 2021 May 4;33(5):1062-1064. doi: 10.1016/j.cmet.2021.03.018. Cell Metab. 2021. PMID: 33951466 Free PMC article. No abstract available.
Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism.
Watts ER, Howden AJ, Morrison T, Sadiku P, Hukelmann J, von Kriegsheim A, Ghesquiere B, Murphy F, Mirchandani AS, Humphries DC, Grecian R, Ryan EM, Coelho P, Blanco GR, Plant TM, Dickinson RS, Finch A, Vermaelen W, Cantrell DA, Whyte MK, Walmsley SR. Watts ER, et al. Among authors: ryan em. J Clin Invest. 2021 May 17;131(10):e134073. doi: 10.1172/JCI134073. J Clin Invest. 2021. PMID: 33822765 Free PMC article.
68 results