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KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.
Pan Y, Han H, Hu H, Wang H, Song Y, Hao Y, Tong X, Patel AS, Misirlioglu S, Tang S, Huang HY, Geng K, Chen T, Karatza A, Sherman F, Labbe KE, Yang F, Chafitz A, Peng C, Guo C, Moreira AL, Velcheti V, Lau SCM, Sui P, Chen H, Diehl JA, Rustgi AK, Bass AJ, Poirier JT, Zhang X, Ji H, Zhang H, Wong KK. Pan Y, et al. Among authors: rustgi ak. Cancer Cell. 2023 Jan 9;41(1):88-105.e8. doi: 10.1016/j.ccell.2022.11.015. Epub 2022 Dec 15. Cancer Cell. 2023. PMID: 36525973 Free PMC article.
Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation.
Mucha B, Qie S, Bajpai S, Tarallo V, Diehl JN, Tedeschi F, Zhou G, Gao Z, Flashner S, Klein-Szanto AJ, Hibshoosh H, Masataka S, Chajewski OS, Majsterek I, Pytel D, Hatzoglou M, Der CJ, Nakagawa H, Bass AJ, Wong KK, Fuchs SY, Rustgi AK, Jankowsky E, Diehl JA. Mucha B, et al. Among authors: rustgi ak. Nat Commun. 2022 Nov 3;13(1):6614. doi: 10.1038/s41467-022-34402-6. Nat Commun. 2022. PMID: 36329064 Free PMC article.
Cancer-Associated Fibroblasts in Esophageal Cancer.
Dunbar KJ, Wong KK, Rustgi AK. Dunbar KJ, et al. Among authors: rustgi ak. Cell Mol Gastroenterol Hepatol. 2024;17(5):687-695. doi: 10.1016/j.jcmgh.2024.01.008. Epub 2024 Jan 19. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38246591 Free PMC article. Review.
Filippo Giancotti (1958-2023).
DePinho R, Massagué J, Manji G, Rustgi AK, Izar B. DePinho R, et al. Among authors: rustgi ak. Nat Cancer. 2023 Oct;4(10):1401-1402. doi: 10.1038/s43018-023-00639-3. Nat Cancer. 2023. PMID: 37770653 No abstract available.
Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy.
Zhang Y, Karagiannis D, Liu H, Lin M, Fang Y, Jiang M, Chen X, Suresh S, Huang H, She J, Shi F, Yang P, El-Rifai W, Zaika A, Oro AE, Rustgi AK, Wang TC, Lu C, Que J. Zhang Y, et al. Among authors: rustgi ak. bioRxiv [Preprint]. 2023 Sep 11:2023.09.09.556982. doi: 10.1101/2023.09.09.556982. bioRxiv. 2023. PMID: 37745439 Free PMC article. Preprint.
p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression.
Efe G, Dunbar KJ, Sugiura K, Cunningham K, Carcamo S, Karaiskos S, Tang Q, Cruz-Acuña R, Resnick-Silverman L, Peura J, Lu C, Hasson D, Klein-Szanto AJ, Taylor AM, Manfredi JJ, Prives C, Rustgi AK. Efe G, et al. Among authors: rustgi ak. Cancer Discov. 2023 Dec 12;13(12):2632-2651. doi: 10.1158/2159-8290.CD-23-0601. Cancer Discov. 2023. PMID: 37676642
396 results