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6 results
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Page 1
Spider venomics: implications for drug discovery.
Future Med Chem. 2014 Oct;6(15):1699-714. doi: 10.4155/fmc.14.103.
Future Med Chem. 2014.
PMID: 25406008
Review.
Spider-venom peptides that target voltage-gated sodium channels: pharmacological tools and potential therapeutic leads.
Klint JK, Senff S, Rupasinghe DB, Er SY, Herzig V, Nicholson GM, King GF.
Klint JK, et al. Among authors: rupasinghe db.
Toxicon. 2012 Sep 15;60(4):478-91. doi: 10.1016/j.toxicon.2012.04.337. Epub 2012 Apr 20.
Toxicon. 2012.
PMID: 22543187
Review.
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Localization of Nav 1.7 in the normal and injured rodent olfactory system indicates a critical role in olfaction, pheromone sensing and immune function.
Rupasinghe DB, Knapp O, Blomster LV, Schmid AB, Adams DJ, King GF, Ruitenberg MJ.
Rupasinghe DB, et al.
Channels (Austin). 2012 Mar-Apr;6(2):103-10. doi: 10.4161/chan.19484. Epub 2012 Mar 1.
Channels (Austin). 2012.
PMID: 22622154
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Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach.
Klint JK, Smith JJ, Vetter I, Rupasinghe DB, Er SY, Senff S, Herzig V, Mobli M, Lewis RJ, Bosmans F, King GF.
Klint JK, et al. Among authors: rupasinghe db.
Br J Pharmacol. 2015 May;172(10):2445-58. doi: 10.1111/bph.13081. Epub 2015 Mar 4.
Br J Pharmacol. 2015.
PMID: 25754331
Free PMC article.
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Mutational analysis of ProTx-I and the novel venom peptide Pe1b provide insight into residues responsible for selective inhibition of the analgesic drug target NaV1.7.
Rupasinghe DB, Herzig V, Vetter I, Dekan Z, Gilchrist J, Bosmans F, Alewood PF, Lewis RJ, King GF.
Rupasinghe DB, et al.
Biochem Pharmacol. 2020 Nov;181:114080. doi: 10.1016/j.bcp.2020.114080. Epub 2020 Jun 6.
Biochem Pharmacol. 2020.
PMID: 32511987
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Rosenbergiella meliponini D21B Isolated from Pollen Pots of the Australian Stingless Bee Tetragonula carbonaria.
Farlow AJ, Rupasinghe DB, Naji KM, Capon RJ, Spiteller D.
Farlow AJ, et al. Among authors: rupasinghe db.
Microorganisms. 2023 Apr 12;11(4):1005. doi: 10.3390/microorganisms11041005.
Microorganisms. 2023.
PMID: 37110428
Free PMC article.
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