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Selective Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibition by the SCH772984 Compound Attenuates In Vitro and In Vivo Inflammatory Responses and Prolongs Survival in Murine Sepsis Models.
Kopczynski M, Rumienczyk I, Kulecka M, Statkiewicz M, Pysniak K, Sandowska-Markiewicz Z, Wojcik-Trechcinska U, Goryca K, Pyziak K, Majewska E, Masiejczyk M, Wojcik-Jaszczynska K, Rzymski T, Bomsztyk K, Ostrowski J, Mikula M. Kopczynski M, et al. Among authors: rumienczyk i. Int J Mol Sci. 2021 Sep 22;22(19):10204. doi: 10.3390/ijms221910204. Int J Mol Sci. 2021. PMID: 34638546 Free PMC article.
Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.
Mikula M, Skrzypczak M, Goryca K, Paczkowska K, Ledwon JK, Statkiewicz M, Kulecka M, Grzelak M, Dabrowska M, Kuklinska U, Karczmarski J, Rumienczyk I, Jastrzebski K, Miaczynska M, Ginalski K, Bomsztyk K, Ostrowski J. Mikula M, et al. Among authors: rumienczyk i. Nucleic Acids Res. 2016 Dec 1;44(21):10150-10164. doi: 10.1093/nar/gkw763. Epub 2016 Sep 1. Nucleic Acids Res. 2016. PMID: 27587583 Free PMC article.
Ectopic overexpression of MCPIP1 impairs adipogenesis by modulating microRNAs.
Losko M, Lichawska-Cieslar A, Kulecka M, Paziewska A, Rumienczyk I, Mikula M, Jura J. Losko M, et al. Among authors: rumienczyk i. Biochim Biophys Acta Mol Cell Res. 2018 Jan;1865(1):186-195. doi: 10.1016/j.bbamcr.2017.09.010. Epub 2017 Sep 20. Biochim Biophys Acta Mol Cell Res. 2018. PMID: 28939056 Free article.
Transcriptomes of human mesenchymal cells isolated from the right ventricle and epicardial fat differ strikingly both directly after isolation and long-term culture.
Stępniewski J, Florczyk-Soluch U, Szade K, Bukowska-Strakova K, Czapla J, Matuszczak S, Jarosz-Biej M, Langrzyk A, Tomczyk M, Rumieńczyk I, Kulecka M, Mikuła M, Ostrowski J, Jaźwa-Kusior A, Zembala M, Józkowicz A, Zembala MO, Dulak J. Stępniewski J, et al. Among authors: rumienczyk i. ESC Heart Fail. 2019 Apr;6(2):351-361. doi: 10.1002/ehf2.12397. Epub 2019 Jan 9. ESC Heart Fail. 2019. PMID: 30623613 Free PMC article.
Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation.
Konieczny P, Lichawska-Cieslar A, Kwiecinska P, Cichy J, Pietrzycka R, Szukala W, Declercq W, Devos M, Paziewska A, Rumienczyk I, Kulecka M, Mikula M, Fu M, Borowczyk J, Santamaria-Babí LF, Jura J. Konieczny P, et al. Among authors: rumienczyk i. J Mol Med (Berl). 2019 Dec;97(12):1669-1684. doi: 10.1007/s00109-019-01853-2. Epub 2019 Nov 30. J Mol Med (Berl). 2019. PMID: 31786670 Free PMC article.
Loss of epidermal MCPIP1 is associated with aggressive squamous cell carcinoma.
Szukala W, Lichawska-Cieslar A, Pietrzycka R, Kulecka M, Rumienczyk I, Mikula M, Chlebicka I, Konieczny P, Dziedzic K, Szepietowski JC, Fontemaggi G, Rys J, Jura J. Szukala W, et al. Among authors: rumienczyk i. J Exp Clin Cancer Res. 2021 Dec 13;40(1):391. doi: 10.1186/s13046-021-02202-3. J Exp Clin Cancer Res. 2021. PMID: 34903245 Free PMC article.
Oncology Drug Repurposing for Sepsis Treatment.
Rumienczyk I, Kulecka M, Statkiewicz M, Ostrowski J, Mikula M. Rumienczyk I, et al. Biomedicines. 2022 Apr 17;10(4):921. doi: 10.3390/biomedicines10040921. Biomedicines. 2022. PMID: 35453671 Free PMC article. Review.
13 results