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A prime/boost DNA/Modified vaccinia virus Ankara vaccine expressing recombinant Leishmania DNA encoding TRYP is safe and immunogenic in outbred dogs, the reservoir of zoonotic visceral leishmaniasis.
Carson C, Antoniou M, Ruiz-Argüello MB, Alcami A, Christodoulou V, Messaritakis I, Blackwell JM, Courtenay O. Carson C, et al. Among authors: ruiz arguello mb. Vaccine. 2009 Feb 11;27(7):1080-6. doi: 10.1016/j.vaccine.2008.11.094. Epub 2008 Dec 16. Vaccine. 2009. PMID: 19095029 Free PMC article. Clinical Trial.
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