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PARP1 Inhibitor Combined With Oxaliplatin Efficiently Suppresses Oxaliplatin Resistance in Gastric Cancer-Derived Organoids via Homologous Recombination and the Base Excision Repair Pathway.
Li H, Wang C, Lan L, Wu W, Evans I, Ruiz EJ, Yan L, Zhou Z, Oliveira JM, Reis RL, Hu Z, Chen W, Behrens A, He Y, Zhang C. Li H, et al. Among authors: ruiz ej. Front Cell Dev Biol. 2021 Aug 23;9:719192. doi: 10.3389/fcell.2021.719192. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34497808 Free PMC article.
ATMIN Is a Tumor Suppressor Gene in Lung Adenocarcinoma.
Foster H, Ruiz EJ, Moore C, Stamp GWH, Nye EL, Li N, Pan Y, He Y, Downward J, Behrens A. Foster H, et al. Among authors: ruiz ej. Cancer Res. 2019 Oct 15;79(20):5159-5166. doi: 10.1158/0008-5472.CAN-19-0647. Epub 2019 Sep 3. Cancer Res. 2019. PMID: 31481498 Free PMC article.
GREM1 is required to maintain cellular heterogeneity in pancreatic cancer.
Lan L, Evan T, Li H, Hussain A, Ruiz EJ, Zaw Thin M, Ferreira RMM, Ps H, Riising EM, Zen Y, Almagro J, Ng KW, Soro-Barrio P, Nelson J, Koifman G, Carvalho J, Nye EL, He Y, Zhang C, Sadanandam A, Behrens A. Lan L, et al. Among authors: ruiz ej. Nature. 2022 Jul;607(7917):163-168. doi: 10.1038/s41586-022-04888-7. Epub 2022 Jun 29. Nature. 2022. PMID: 35768509
LUBAC determines chemotherapy resistance in squamous cell lung cancer.
Ruiz EJ, Diefenbacher ME, Nelson JK, Sancho R, Pucci F, Chakraborty A, Moreno P, Annibaldi A, Liccardi G, Encheva V, Mitter R, Rosenfeldt M, Snijders AP, Meier P, Calzado MA, Behrens A. Ruiz EJ, et al. J Exp Med. 2019 Feb 4;216(2):450-465. doi: 10.1084/jem.20180742. Epub 2019 Jan 14. J Exp Med. 2019. PMID: 30642944 Free PMC article.
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma.
Ruiz EJ, Pinto-Fernandez A, Turnbull AP, Lan L, Charlton TM, Scott HC, Damianou A, Vere G, Riising EM, Da Costa C, Krajewski WW, Guerin D, Kearns JD, Ioannidis S, Katz M, McKinnon C, O'Connell J, Moncaut N, Rosewell I, Nye E, Jones N, Heride C, Gersch M, Wu M, Dinsmore CJ, Hammonds TR, Kim S, Komander D, Urbe S, Clague MJ, Kessler BM, Behrens A. Ruiz EJ, et al. Elife. 2021 Oct 12;10:e71596. doi: 10.7554/eLife.71596. Elife. 2021. PMID: 34636321 Free PMC article.
30 results