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H1:IC31 vaccination is safe and induces long-lived TNF-α+IL-2+CD4 T cell responses in M. tuberculosis infected and uninfected adolescents: A randomized trial.
Mearns H, Geldenhuys HD, Kagina BM, Musvosvi M, Little F, Ratangee F, Mahomed H, Hanekom WA, Hoff ST, Ruhwald M, Kromann I, Bang P, Hatherill M, Andersen P, Scriba TJ; THYB04 study group. Mearns H, et al. Among authors: ruhwald m. Vaccine. 2017 Jan 3;35(1):132-141. doi: 10.1016/j.vaccine.2016.11.023. Epub 2016 Nov 18. Vaccine. 2017. PMID: 27866772 Clinical Trial.
Development of a one-step probe based molecular assay for rapid immunodiagnosis of infection with M. tuberculosis using dried blood spots.
Blauenfeldt T, Heyckendorf J, Graff Jensen S, Lange C, Drabe C, Hermansen TS, de Thurah L, Lillebaek T, Eugen-Olsen J, Seersholm N, Hoff S, Bonde J, Ruhwald M. Blauenfeldt T, et al. Among authors: ruhwald m. PLoS One. 2014 Sep 3;9(9):e105628. doi: 10.1371/journal.pone.0105628. eCollection 2014. PLoS One. 2014. PMID: 25184553 Free PMC article.
A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis-specific T-cell responses in human.
van Dissel JT, Joosten SA, Hoff ST, Soonawala D, Prins C, Hokey DA, O'Dee DM, Graves A, Thierry-Carstensen B, Andreasen LV, Ruhwald M, de Visser AW, Agger EM, Ottenhoff TH, Kromann I, Andersen P. van Dissel JT, et al. Among authors: ruhwald m. Vaccine. 2014 Dec 12;32(52):7098-107. doi: 10.1016/j.vaccine.2014.10.036. Epub 2014 Oct 30. Vaccine. 2014. PMID: 25454872 Free article. Clinical Trial.
TB vaccines in clinical development.
Ginsberg AM, Ruhwald M, Mearns H, McShane H. Ginsberg AM, et al. Among authors: ruhwald m. Tuberculosis (Edinb). 2016 Aug;99 Suppl 1:S16-20. doi: 10.1016/j.tube.2016.05.013. Epub 2016 Jun 16. Tuberculosis (Edinb). 2016. PMID: 27470538
Safety and efficacy of the C-Tb skin test to diagnose Mycobacterium tuberculosis infection, compared with an interferon γ release assay and the tuberculin skin test: a phase 3, double-blind, randomised, controlled trial.
Ruhwald M, Aggerbeck H, Gallardo RV, Hoff ST, Villate JI, Borregaard B, Martinez JA, Kromann I, Penas A, Anibarro LL, de Souza-Galvão ML, Sánchez F, Rodrigo-Pendás JÁ, Noguera-Julian A, Martínez-Lacasa X, Tuñez MV, Fernández VL, Millet JP, Moreno A, Cobos N, Miró JM, Roldan L, Orcau A, Andersen P, Caylá JA; TESEC Working Group. Ruhwald M, et al. Lancet Respir Med. 2017 Apr;5(4):259-268. doi: 10.1016/S2213-2600(16)30436-2. Epub 2017 Feb 1. Lancet Respir Med. 2017. PMID: 28159608 Clinical Trial.
138 results