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A new class of anthelmintics effective against drug-resistant nematodes.
Kaminsky R, Ducray P, Jung M, Clover R, Rufener L, Bouvier J, Weber SS, Wenger A, Wieland-Berghausen S, Goebel T, Gauvry N, Pautrat F, Skripsky T, Froelich O, Komoin-Oka C, Westlund B, Sluder A, Mäser P. Kaminsky R, et al. Among authors: rufener l. Nature. 2008 Mar 13;452(7184):176-80. doi: 10.1038/nature06722. Nature. 2008. PMID: 18337814
Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis.
Bah GS, Schneckener S, Hahnel SR, Bayang NH, Fieseler H, Schmuck GM, Krebber R, Sarr A, Terjung C, Ngangyung HF, Ekale DD, Mfopit YM, Rufener L, Graham-Brown J, Tanya VN, Glenschek-Sieberth M, Kulke D, Makepeace BL. Bah GS, et al. Among authors: rufener l. PLoS Pathog. 2021 Jun 2;17(6):e1009601. doi: 10.1371/journal.ppat.1009601. eCollection 2021 Jun. PLoS Pathog. 2021. PMID: 34077488 Free PMC article.
Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions.
Kotze AC, Hunt PW, Skuce P, von Samson-Himmelstjerna G, Martin RJ, Sager H, Krücken J, Hodgkinson J, Lespine A, Jex AR, Gilleard JS, Beech RN, Wolstenholme AJ, Demeler J, Robertson AP, Charvet CL, Neveu C, Kaminsky R, Rufener L, Alberich M, Menez C, Prichard RK. Kotze AC, et al. Among authors: rufener l. Int J Parasitol Drugs Drug Resist. 2014 Aug 13;4(3):164-84. doi: 10.1016/j.ijpddr.2014.07.007. eCollection 2014 Dec. Int J Parasitol Drugs Drug Resist. 2014. PMID: 25516826 Free PMC article. Review.
19 results