Ruderman NB - Search Results

1

AMP-activated Protein Kinase (AMPK): Does This Master Regulator of Cellular Energy State Distinguish Insulin Sensitive from Insulin Resistant Obesity?

Xu XJ, Valentine RJ, Ruderman NB. Xu XJ, et al. Among authors: ruderman nb. Curr Obes Rep. 2014 Jun 1;3(2):248-55. doi: 10.1007/s13679-014-0095-x. Curr Obes Rep. 2014. PMID: 24891985 Free PMC article.

2

Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue.

Xu XJ, Gauthier MS, Hess DT, Apovian CM, Cacicedo JM, Gokce N, Farb M, Valentine RJ, Ruderman NB. Xu XJ, et al. Among authors: ruderman nb. J Lipid Res. 2012 Apr;53(4):792-801. doi: 10.1194/jlr.P022905. Epub 2012 Feb 8. J Lipid Res. 2012. PMID: 22323564 Free PMC article.

3

What distinguishes adipose tissue of severely obese humans who are insulin sensitive and resistant?

Xu XJ, Pories WJ, Dohm LG, Ruderman NB. Xu XJ, et al. Among authors: ruderman nb. Curr Opin Lipidol. 2013 Feb;24(1):49-56. doi: 10.1097/MOL.0b013e32835b465b. Curr Opin Lipidol. 2013. PMID: 23298959 Free PMC article. Review.

4

AMPK activation: a therapeutic target for type 2 diabetes?

Coughlan KA, Valentine RJ, Ruderman NB, Saha AK. Coughlan KA, et al. Among authors: ruderman nb. Diabetes Metab Syndr Obes. 2014 Jun 24;7:241-53. doi: 10.2147/DMSO.S43731. eCollection 2014. Diabetes Metab Syndr Obes. 2014. PMID: 25018645 Free PMC article. Review.

5

Nutrient Excess in AMPK Downregulation and Insulin Resistance.

Coughlan KA, Valentine RJ, Ruderman NB, Saha AK. Coughlan KA, et al. Among authors: ruderman nb. J Endocrinol Diabetes Obes. 2013 Jul-Sep;1(1):1008. J Endocrinol Diabetes Obes. 2013. PMID: 26120590 Free PMC article.

6

Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle.

Saha AK, Xu XJ, Lawson E, Deoliveira R, Brandon AE, Kraegen EW, Ruderman NB. Saha AK, et al. Among authors: ruderman nb. Diabetes. 2010 Oct;59(10):2426-34. doi: 10.2337/db09-1870. Epub 2010 Aug 3. Diabetes. 2010. PMID: 20682696 Free PMC article.

7

Insulin resistance due to nutrient excess: is it a consequence of AMPK downregulation?

Saha AK, Xu XJ, Balon TW, Brandon A, Kraegen EW, Ruderman NB. Saha AK, et al. Among authors: ruderman nb. Cell Cycle. 2011 Oct 15;10(20):3447-51. doi: 10.4161/cc.10.20.17886. Cell Cycle. 2011. PMID: 22067655 Free PMC article. Review.

8

A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells.

Nelson LE, Valentine RJ, Cacicedo JM, Gauthier MS, Ido Y, Ruderman NB. Nelson LE, et al. Among authors: ruderman nb. Am J Physiol Cell Physiol. 2012 Jul 1;303(1):C4-C13. doi: 10.1152/ajpcell.00296.2011. Epub 2012 Feb 29. Am J Physiol Cell Physiol. 2012. PMID: 22378745 Free PMC article.

9

Insulin inhibits AMPK activity and phosphorylates AMPK Ser⁴⁸⁵/⁴⁹¹ through Akt in hepatocytes, myotubes and incubated rat skeletal muscle.

Valentine RJ, Coughlan KA, Ruderman NB, Saha AK. Valentine RJ, et al. Among authors: ruderman nb. Arch Biochem Biophys. 2014 Nov 15;562:62-9. doi: 10.1016/j.abb.2014.08.013. Epub 2014 Aug 27. Arch Biochem Biophys. 2014. PMID: 25172224 Free PMC article.

10

Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats.

Coughlan KA, Balon TW, Valentine RJ, Petrocelli R, Schultz V, Brandon A, Cooney GJ, Kraegen EW, Ruderman NB, Saha AK. Coughlan KA, et al. Among authors: ruderman nb. PLoS One. 2015 May 21;10(5):e0127388. doi: 10.1371/journal.pone.0127388. eCollection 2015. PLoS One. 2015. PMID: 25996822 Free PMC article.

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