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The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.
Carmona-Gutierrez D, Zimmermann A, Kainz K, Pietrocola F, Chen G, Maglioni S, Schiavi A, Nah J, Mertel S, Beuschel CB, Castoldi F, Sica V, Trausinger G, Raml R, Sommer C, Schroeder S, Hofer SJ, Bauer MA, Pendl T, Tadic J, Dammbrueck C, Hu Z, Ruckenstuhl C, Eisenberg T, Durand S, Bossut N, Aprahamian F, Abdellatif M, Sedej S, Enot DP, Wolinski H, Dengjel J, Kepp O, Magnes C, Sinner F, Pieber TR, Sadoshima J, Ventura N, Sigrist SJ, Kroemer G, Madeo F. Carmona-Gutierrez D, et al. Among authors: ruckenstuhl c. Nat Commun. 2019 Feb 19;10(1):651. doi: 10.1038/s41467-019-08555-w. Nat Commun. 2019. PMID: 30783116 Free PMC article.
Endonuclease G regulates budding yeast life and death.
Büttner S, Eisenberg T, Carmona-Gutierrez D, Ruli D, Knauer H, Ruckenstuhl C, Sigrist C, Wissing S, Kollroser M, Fröhlich KU, Sigrist S, Madeo F. Büttner S, et al. Among authors: ruckenstuhl c. Mol Cell. 2007 Jan 26;25(2):233-46. doi: 10.1016/j.molcel.2006.12.021. Mol Cell. 2007. PMID: 17244531 Free article.
Induction of autophagy by spermidine promotes longevity.
Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Fröhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, Madeo F. Eisenberg T, et al. Among authors: ruckenstuhl c. Nat Cell Biol. 2009 Nov;11(11):1305-14. doi: 10.1038/ncb1975. Epub 2009 Oct 4. Nat Cell Biol. 2009. PMID: 19801973
Spermidine: a novel autophagy inducer and longevity elixir.
Madeo F, Eisenberg T, Büttner S, Ruckenstuhl C, Kroemer G. Madeo F, et al. Among authors: ruckenstuhl c. Autophagy. 2010 Jan;6(1):160-2. doi: 10.4161/auto.6.1.10600. Autophagy. 2010. PMID: 20110777 Review.
Cell death in yeast: growing applications of a dying buddy.
Carmona-Gutierrez D, Ruckenstuhl C, Bauer MA, Eisenberg T, Büttner S, Madeo F. Carmona-Gutierrez D, et al. Among authors: ruckenstuhl c. Cell Death Differ. 2010 May;17(5):733-4. doi: 10.1038/cdd.2010.10. Cell Death Differ. 2010. PMID: 20383156 No abstract available.
Identification of evolutionarily conserved genetic regulators of cellular aging.
Laschober GT, Ruli D, Hofer E, Muck C, Carmona-Gutierrez D, Ring J, Hutter E, Ruckenstuhl C, Micutkova L, Brunauer R, Jamnig A, Trimmel D, Herndler-Brandstetter D, Brunner S, Zenzmaier C, Sampson N, Breitenbach M, Fröhlich KU, Grubeck-Loebenstein B, Berger P, Wieser M, Grillari-Voglauer R, Thallinger GG, Grillari J, Trajanoski Z, Madeo F, Lepperdinger G, Jansen-Dürr P. Laschober GT, et al. Among authors: ruckenstuhl c. Aging Cell. 2010 Dec;9(6):1084-97. doi: 10.1111/j.1474-9726.2010.00637.x. Epub 2010 Oct 28. Aging Cell. 2010. PMID: 20883526 Free PMC article.
The propeptide of yeast cathepsin D inhibits programmed necrosis.
Carmona-Gutiérrez D, Bauer MA, Ring J, Knauer H, Eisenberg T, Büttner S, Ruckenstuhl C, Reisenbichler A, Magnes C, Rechberger GN, Birner-Gruenberger R, Jungwirth H, Fröhlich KU, Sinner F, Kroemer G, Madeo F. Carmona-Gutiérrez D, et al. Among authors: ruckenstuhl c. Cell Death Dis. 2011 May 19;2(5):e161. doi: 10.1038/cddis.2011.43. Cell Death Dis. 2011. PMID: 21593793 Free PMC article.
51 results