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Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model.
Roel M, Rubiolo JA, Guerra-Varela J, Silva SB, Thomas OP, Cabezas-Sainz P, Sánchez L, López R, Botana LM. Roel M, et al. Among authors: rubiolo ja. Oncotarget. 2016 Dec 13;7(50):83071-83087. doi: 10.18632/oncotarget.13068. Oncotarget. 2016. PMID: 27825113 Free PMC article.
Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells.
Valle S, Alcalá S, Martin-Hijano L, Cabezas-Sáinz P, Navarro D, Muñoz ER, Yuste L, Tiwary K, Walter K, Ruiz-Cañas L, Alonso-Nocelo M, Rubiolo JA, González-Arnay E, Heeschen C, Garcia-Bermejo L, Hermann PC, Sánchez L, Sancho P, Fernández-Moreno MÁ, Sainz B Jr. Valle S, et al. Among authors: rubiolo ja. Nat Commun. 2020 Oct 16;11(1):5265. doi: 10.1038/s41467-020-18954-z. Nat Commun. 2020. PMID: 33067432 Free PMC article.
Inhibition of Mitochondrial Dynamics Preferentially Targets Pancreatic Cancer Cells with Enhanced Tumorigenic and Invasive Potential.
Courtois S, de Luxán-Delgado B, Penin-Peyta L, Royo-García A, Parejo-Alonso B, Jagust P, Alcalá S, Rubiolo JA, Sánchez L, Sainz B Jr, Heeschen C, Sancho P. Courtois S, et al. Among authors: rubiolo ja. Cancers (Basel). 2021 Feb 9;13(4):698. doi: 10.3390/cancers13040698. Cancers (Basel). 2021. PMID: 33572276 Free PMC article.
Manganese(I) tricarbonyl complexes as potential anticancer agents.
Lenis-Rojas OA, Carvalho B, Cabral R, Silva M, Friães S, Roma-Rodrigues C, Meireles MSH, Gomes CSB, Fernández JAA, Vila SF, Rubiolo JA, Sanchez L, Baptista PV, Fernandes AR, Royo B. Lenis-Rojas OA, et al. Among authors: rubiolo ja. J Biol Inorg Chem. 2022 Feb;27(1):49-64. doi: 10.1007/s00775-021-01910-7. Epub 2021 Oct 29. J Biol Inorg Chem. 2022. PMID: 34713347
A continuous in silico learning strategy to identify safety liabilities in compounds used in the leather and textile industry.
March-Vila E, Ferretti G, Terricabras E, Ardao I, Brea JM, Varela MJ, Arana Á, Rubiolo JA, Sanz F, Loza MI, Sánchez L, Alonso H, Pastor M. March-Vila E, et al. Among authors: rubiolo ja. Arch Toxicol. 2023 Apr;97(4):1091-1111. doi: 10.1007/s00204-023-03459-7. Epub 2023 Feb 12. Arch Toxicol. 2023. PMID: 36781432 Free PMC article.
47 results