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Risk factors for developing ventilator-associated lower respiratory tract infection in patients with severe COVID-19: a multinational, multicentre study, prospective, observational study.
Sci Rep. 2023 Apr 21;13(1):6553. doi: 10.1038/s41598-023-32265-5.
Sci Rep. 2023.
PMID: 37085552
Free PMC article.
A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors.
Ruiz JF, Kedziora K, Keogh B, Maguire J, Reilly M, Windle H, Kelleher DP, Gilmer JF.
Ruiz JF, et al.
Bioorg Med Chem Lett. 2011 Nov 15;21(22):6636-40. doi: 10.1016/j.bmcl.2011.09.071. Epub 2011 Sep 22.
Bioorg Med Chem Lett. 2011.
PMID: 21983446
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Deploying unsupervised clustering analysis to derive clinical phenotypes and risk factors associated with mortality risk in 2022 critically ill patients with COVID-19 in Spain.
Rodríguez A, Ruiz-Botella M, Martín-Loeches I, Jimenez Herrera M, Solé-Violan J, Gómez J, Bodí M, Trefler S, Papiol E, Díaz E, Suberviola B, Vallverdu M, Mayor-Vázquez E, Albaya Moreno A, Canabal Berlanga A, Sánchez M, Del Valle Ortíz M, Ballesteros JC, Martín Iglesias L, Marín-Corral J, López Ramos E, Hidalgo Valverde V, Vidaur Tello LV, Sancho Chinesta S, Gonzáles de Molina FJ, Herrero García S, Sena Pérez CC, Pozo Laderas JC, Rodríguez García R, Estella A, Ferrer R; COVID-19 SEMICYUC Working Group.
Rodríguez A, et al.
Crit Care. 2021 Feb 15;25(1):63. doi: 10.1186/s13054-021-03487-8.
Crit Care. 2021.
PMID: 33588914
Free PMC article.
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Investigation into drug release from colon-specific azoreductase-activated steroid prodrugs using in-vitro models.
Ruiz JF, Kedziora K, Windle H, Kelleher DP, Gilmer JF.
Ruiz JF, et al.
J Pharm Pharmacol. 2011 Jun;63(6):806-16. doi: 10.1111/j.2042-7158.2011.01289.x. Epub 2011 May 3.
J Pharm Pharmacol. 2011.
PMID: 21585379
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Structure requirements for anaerobe processing of azo compounds: implications for prodrug design.
Gavin J, Ruiz JF, Kedziora K, Windle H, Kelleher DP, Gilmer JF.
Gavin J, et al.
Bioorg Med Chem Lett. 2012 Dec 15;22(24):7647-52. doi: 10.1016/j.bmcl.2012.10.014. Epub 2012 Oct 11.
Bioorg Med Chem Lett. 2012.
PMID: 23122822
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Design, synthesis, and pharmacological effects of a cyclization-activated steroid prodrug for colon targeting in inflammatory bowel disease.
Ruiz JF, Radics G, Windle H, Serra HO, Simplício AL, Kedziora K, Fallon PG, Kelleher DP, Gilmer JF.
Ruiz JF, et al.
J Med Chem. 2009 May 28;52(10):3205-11. doi: 10.1021/jm8016317.
J Med Chem. 2009.
PMID: 19397323
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