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PRMT5 activates AKT via methylation to promote tumor metastasis.
Nat Commun. 2022 Jul 8;13(1):3955. doi: 10.1038/s41467-022-31645-1.
Nat Commun. 2022.
PMID: 35803962
Free PMC article.
Systematic review of the receptor tyrosine kinase superfamily in neuroblastoma pathophysiology.
Rozen EJ, Shohet JM.
Rozen EJ, et al.
Cancer Metastasis Rev. 2022 Mar;41(1):33-52. doi: 10.1007/s10555-021-10001-7. Epub 2021 Oct 30.
Cancer Metastasis Rev. 2022.
PMID: 34716856
Free PMC article.
Review.
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Blockade of Discoidin Domain Receptor Signaling with Sitravatinib Reveals DDR2 as a Mediator of Neuroblastoma Pathogenesis and Metastasis.
Rozen EJ, Frantz W, Wigglesworth K, Vessella T, Zhou HS, Shohet JM.
Rozen EJ, et al.
Mol Cancer Ther. 2024 Apr 27. doi: 10.1158/1535-7163.MCT-23-0741. Online ahead of print.
Mol Cancer Ther. 2024.
PMID: 38670553
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DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells.
Rozen EJ, Roewenstrunk J, Barallobre MJ, Di Vona C, Jung C, Figueiredo AF, Luna J, Fillat C, Arbonés ML, Graupera M, Valverde MA, de la Luna S.
Rozen EJ, et al.
Cell Rep. 2018 May 8;23(6):1867-1878. doi: 10.1016/j.celrep.2018.04.008.
Cell Rep. 2018.
PMID: 29742440
Free article.
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Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons.
Encinas M, Rozen EJ, Dolcet X, Jain S, Comella JX, Milbrandt J, Johnson EM Jr.
Encinas M, et al. Among authors: rozen ej.
Cell Death Differ. 2008 Sep;15(9):1510-21. doi: 10.1038/cdd.2008.76. Epub 2008 May 23.
Cell Death Differ. 2008.
PMID: 18497757
Free PMC article.
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Loss of Sprouty1 rescues renal agenesis caused by Ret mutation.
Rozen EJ, Schmidt H, Dolcet X, Basson MA, Jain S, Encinas M.
Rozen EJ, et al.
J Am Soc Nephrol. 2009 Feb;20(2):255-9. doi: 10.1681/ASN.2008030267. Epub 2008 Dec 3.
J Am Soc Nephrol. 2009.
PMID: 19056869
Free PMC article.
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A Novel Druggable Dual-Specificity tYrosine-Regulated Kinase3/Calmodulin Kinase-like Vesicle-Associated Signaling Module with Therapeutic Implications in Neuroblastoma.
Rozen EJ, Wigglesworth K, Shohet JM.
Rozen EJ, et al.
Biomedicines. 2024 Jan 16;12(1):197. doi: 10.3390/biomedicines12010197.
Biomedicines. 2024.
PMID: 38255303
Free PMC article.
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RUN(X) out of blood: emerging RUNX1 functions beyond hematopoiesis and links to Down syndrome.
Rozen EJ, Ozeroff CD, Allen MA.
Rozen EJ, et al.
Hum Genomics. 2023 Sep 5;17(1):83. doi: 10.1186/s40246-023-00531-2.
Hum Genomics. 2023.
PMID: 37670378
Free PMC article.
Review.
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