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PRMT5 activates AKT via methylation to promote tumor metastasis.
Huang L, Zhang XO, Rozen EJ, Sun X, Sallis B, Verdejo-Torres O, Wigglesworth K, Moon D, Huang T, Cavaretta JP, Wang G, Zhang L, Shohet JM, Lee MM, Wu Q. Huang L, et al. Among authors: rozen ej. Nat Commun. 2022 Jul 8;13(1):3955. doi: 10.1038/s41467-022-31645-1. Nat Commun. 2022. PMID: 35803962 Free PMC article.
DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells.
Rozen EJ, Roewenstrunk J, Barallobre MJ, Di Vona C, Jung C, Figueiredo AF, Luna J, Fillat C, Arbonés ML, Graupera M, Valverde MA, de la Luna S. Rozen EJ, et al. Cell Rep. 2018 May 8;23(6):1867-1878. doi: 10.1016/j.celrep.2018.04.008. Cell Rep. 2018. PMID: 29742440 Free article.
Loss of Sprouty1 rescues renal agenesis caused by Ret mutation.
Rozen EJ, Schmidt H, Dolcet X, Basson MA, Jain S, Encinas M. Rozen EJ, et al. J Am Soc Nephrol. 2009 Feb;20(2):255-9. doi: 10.1681/ASN.2008030267. Epub 2008 Dec 3. J Am Soc Nephrol. 2009. PMID: 19056869 Free PMC article.