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Diphtheria toxin activates ribotoxic stress and NLRP1 inflammasome-driven pyroptosis.
Robinson KS, Toh GA, Firdaus MJ, Tham KC, Rozario P, Lim CK, Toh YX, Lau ZH, Binder SC, Mayer J, Bonnard C, Schmidt FI, Common JEA, Zhong FL. Robinson KS, et al. Among authors: rozario p. J Exp Med. 2023 Oct 2;220(10):e20230105. doi: 10.1084/jem.20230105. Epub 2023 Aug 29. J Exp Med. 2023. PMID: 37642997 Free PMC article.
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome.
Robinson KS, Toh GA, Rozario P, Chua R, Bauernfried S, Sun Z, Firdaus MJ, Bayat S, Nadkarni R, Poh ZS, Tham KC, Harapas CR, Lim CK, Chu W, Tay CWS, Tan KY, Zhao T, Bonnard C, Sobota R, Connolly JE, Common J, Masters SL, Chen KW, Ho L, Wu B, Hornung V, Zhong FL. Robinson KS, et al. Among authors: rozario p. Science. 2022 Jul 15;377(6603):328-335. doi: 10.1126/science.abl6324. Epub 2022 Jul 14. Science. 2022. PMID: 35857590 Free PMC article.
Mechanistic basis for potassium efflux-driven activation of the human NLRP1 inflammasome.
Rozario P, Pinilla M, Gorse L, Vind AC, Robinson KS, Toh GA, Firdaus MJ, Martínez JF, Kerk SK, Lin Z, Chambers JC, Bekker-Jensen S, Meunier E, Zhong F. Rozario P, et al. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2309579121. doi: 10.1073/pnas.2309579121. Epub 2024 Jan 4. Proc Natl Acad Sci U S A. 2024. PMID: 38175865
Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases.
Ahn M, Chen VC, Rozario P, Ng WL, Kong PS, Sia WR, Kang AEZ, Su Q, Nguyen LH, Zhu F, Chan WOY, Tan CW, Cheong WS, Hey YY, Foo R, Guo F, Lim YT, Li X, Chia WN, Sobota RM, Fu NY, Irving AT, Wang LF. Ahn M, et al. Among authors: rozario p. Cell. 2023 May 11;186(10):2144-2159.e22. doi: 10.1016/j.cell.2023.03.036. Cell. 2023. PMID: 37172565
A Comprehensive Review of Machine Learning Used to Combat COVID-19.
Gomes R, Kamrowski C, Langlois J, Rozario P, Dircks I, Grottodden K, Martinez M, Tee WZ, Sargeant K, LaFleur C, Haley M. Gomes R, et al. Among authors: rozario p. Diagnostics (Basel). 2022 Jul 31;12(8):1853. doi: 10.3390/diagnostics12081853. Diagnostics (Basel). 2022. PMID: 36010204 Free PMC article. Review.
Robust dengue virus infection in bat cells and limited innate immune responses coupled with positive serology from bats in IndoMalaya and Australasia.
Irving AT, Rozario P, Kong PS, Luko K, Gorman JJ, Hastie ML, Chia WN, Mani S, Lee BP, Smith GJD, Mendenhall IH, Larman HB, Elledge SJ, Wang LF. Irving AT, et al. Among authors: rozario p. Cell Mol Life Sci. 2020 Apr;77(8):1607-1622. doi: 10.1007/s00018-019-03242-x. Epub 2019 Jul 27. Cell Mol Life Sci. 2020. PMID: 31352533
28 results