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Microglial expression of CD83 governs cellular activation and restrains neuroinflammation in experimental autoimmune encephalomyelitis.
Sinner P, Peckert-Maier K, Mohammadian H, Kuhnt C, Draßner C, Panagiotakopoulou V, Rauber S, Linnerbauer M, Haimon Z, Royzman D, Kronenberg-Versteeg D, Ramming A, Steinkasserer A, Wild AB. Sinner P, et al. Among authors: royzman d. Nat Commun. 2023 Aug 1;14(1):4601. doi: 10.1038/s41467-023-40370-2. Nat Commun. 2023. PMID: 37528070 Free PMC article.
The CD83 Molecule - An Important Immune Checkpoint.
Grosche L, Knippertz I, König C, Royzman D, Wild AB, Zinser E, Sticht H, Muller YA, Steinkasserer A, Lechmann M. Grosche L, et al. Among authors: royzman d. Front Immunol. 2020 Apr 17;11:721. doi: 10.3389/fimmu.2020.00721. eCollection 2020. Front Immunol. 2020. PMID: 32362900 Free PMC article. Review.
Siglec-15 on Osteoclasts Is Crucial for Bone Erosion in Serum-Transfer Arthritis.
Korn MA, Schmitt H, Angermüller S, Chambers D, Seeling M, Lux UT, Brey S, Royzman D, Brückner C, Popp V, Percivalle E, Bäuerle T, Zinser E, Winkler TH, Steinkasserer A, Nimmerjahn F, Nitschke L. Korn MA, et al. Among authors: royzman d. J Immunol. 2020 Nov 15;205(10):2595-2605. doi: 10.4049/jimmunol.2000472. Epub 2020 Oct 5. J Immunol. 2020. PMID: 33020147
Pre-incubation of corneal donor tissue with sCD83 improves graft survival via the induction of alternatively activated macrophages and tolerogenic dendritic cells.
Peckert-Maier K, Schönberg A, Wild AB, Royzman D, Braun G, Stich L, Hadrian K, Tripal P, Cursiefen C, Steinkasserer A, Zinser E, Bock F. Peckert-Maier K, et al. Among authors: royzman d. Am J Transplant. 2022 Feb;22(2):438-454. doi: 10.1111/ajt.16824. Epub 2021 Sep 20. Am J Transplant. 2022. PMID: 34467638 Free article.
The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis.
Royzman D, Andreev D, Stich L, Peckert-Maier K, Wild AB, Zinser E, Mühl-Zürbes P, Jones E, Adam S, Frey S, Fuchs M, Kunz M, Bäuerle T, Nagel L, Schett G, Bozec A, Steinkasserer A. Royzman D, et al. Front Immunol. 2022 Aug 8;13:936995. doi: 10.3389/fimmu.2022.936995. eCollection 2022. Front Immunol. 2022. PMID: 36003376 Free PMC article.
Soluble CD83 improves and accelerates wound healing by the induction of pro-resolving macrophages.
Royzman D, Peckert-Maier K, Stich L, König C, Wild AB, Tauchi M, Ostalecki C, Kiesewetter F, Seyferth S, Lee G, Eming SA, Fuchs M, Kunz M, Stürmer EK, Peters EMJ, Berking C, Zinser E, Steinkasserer A. Royzman D, et al. Front Immunol. 2022 Sep 30;13:1012647. doi: 10.3389/fimmu.2022.1012647. eCollection 2022. Front Immunol. 2022. PMID: 36248909 Free PMC article.
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