Roush WR - Search Results

1

Molecular Modeling of ABHD5 Structure and Ligand Recognition.

Shahoei R, Pangeni S, Sanders MA, Zhang H, Mladenovic-Lucas L, Roush WR, Halvorsen G, Kelly CV, Granneman JG, Huang YM. Shahoei R, et al. Among authors: roush wr. Front Mol Biosci. 2022 Jun 28;9:935375. doi: 10.3389/fmolb.2022.935375. eCollection 2022. Front Mol Biosci. 2022. PMID: 35836935 Free PMC article.

2

Intramolecular Diels-Alder reactions of siloxacyclopentene constrained trienes.

Halvorsen GT, Roush WR. Halvorsen GT, et al. Among authors: roush wr. Org Lett. 2007 May 24;9(11):2243-6. doi: 10.1021/ol070858u. Epub 2007 May 5. Org Lett. 2007. PMID: 17480094 Free PMC article.

3

Siloxacyclopentenes as dienophile-linked directing groups in intramolecular Diels-Alder reactions.

Halvorsen GT, Roush WR. Halvorsen GT, et al. Among authors: roush wr. Org Lett. 2008 Nov 20;10(22):5313-6. doi: 10.1021/ol802266s. Epub 2008 Oct 28. Org Lett. 2008. PMID: 18954061 Free PMC article.

4

Stereoselective Synthesis of the Decahydrofluorene Core of the Hirsutellones.

Halvorsen GT, Roush WR. Halvorsen GT, et al. Among authors: roush wr. Tetrahedron Lett. 2011 Apr 27;52(17):2072-2075. doi: 10.1016/j.tetlet.2010.10.111. Tetrahedron Lett. 2011. PMID: 21503271 Free PMC article.

5

Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle.

Sanders MA, Madoux F, Mladenovic L, Zhang H, Ye X, Angrish M, Mottillo EP, Caruso JA, Halvorsen G, Roush WR, Chase P, Hodder P, Granneman JG. Sanders MA, et al. Among authors: roush wr. Cell Metab. 2015 Nov 3;22(5):851-60. doi: 10.1016/j.cmet.2015.08.023. Epub 2015 Sep 24. Cell Metab. 2015. PMID: 26411340 Free PMC article.

6

Novel Pharmacological Probes Reveal ABHD5 as a Locus of Lipolysis Control in White and Brown Adipocytes.

Rondini EA, Mladenovic-Lucas L, Roush WR, Halvorsen GT, Green AE, Granneman JG. Rondini EA, et al. Among authors: roush wr. J Pharmacol Exp Ther. 2017 Dec;363(3):367-376. doi: 10.1124/jpet.117.243253. Epub 2017 Sep 19. J Pharmacol Exp Ther. 2017. PMID: 28928121 Free PMC article.

7

The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis.

Torres S, Brol MJ, Magdaleno F, Schierwagen R, Uschner FE, Klein S, Ortiz C, Tyc O, Bachtler N, Stunden J, Bertheloot D, Kitanovic A, Sanchez B, Schrum J, Roush WR, Franchi L, Byth K, Latz E, Trebicka J. Torres S, et al. Among authors: roush wr. Front Mol Biosci. 2021 Aug 13;8:715765. doi: 10.3389/fmolb.2021.715765. eCollection 2021. Front Mol Biosci. 2021. PMID: 34513923 Free PMC article.

8

Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation.

Choi JY, Plummer MS, Starr J, Desbonnet CR, Soutter H, Chang J, Miller JR, Dillman K, Miller AA, Roush WR. Choi JY, et al. Among authors: roush wr. J Med Chem. 2012 Jan 26;55(2):852-70. doi: 10.1021/jm201349f. Epub 2012 Jan 13. J Med Chem. 2012. PMID: 22243413 Free PMC article.

9

Antiproliferation activity of a small molecule repressor of liver receptor homolog 1.

Corzo CA, Mari Y, Chang MR, Khan T, Kuruvilla D, Nuhant P, Kumar N, West GM, Duckett DR, Roush WR, Griffin PR. Corzo CA, et al. Among authors: roush wr. Mol Pharmacol. 2015 Feb;87(2):296-304. doi: 10.1124/mol.114.095554. Epub 2014 Dec 3. Mol Pharmacol. 2015. PMID: 25473120 Free PMC article.

10

Structure Based Design of CYP51 Inhibitors.

Choi JY, Roush WR. Choi JY, et al. Among authors: roush wr. Curr Top Med Chem. 2017;17(1):30-39. doi: 10.2174/1568026616666160719164933. Curr Top Med Chem. 2017. PMID: 27449014 Review.

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