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Multi-Maintenance Olaparib Therapy in Relapsed, Germline BRCA1/2-Mutant High-Grade Serous Ovarian Cancer (MOLTO): A Phase II Trial.
Morgan RD, Clamp AR, White DJ, Price M, Burghel GJ, Ryder WDJ, Mahmood RD, Murphy AD, Hasan J, Mitchell CL, Salih Z, Wheeler C, Buckley E, Truelove J, King G, Ainaoui Y, Bhaskar SS, Shaw J, Evans DGR, Kilerci B, Pearce SP, Brady G, Dive C, O'Connor JPB, Wallace AJ, Rothwell DG, Edmondson RJ, Jayson GC. Morgan RD, et al. Among authors: rothwell dg. Clin Cancer Res. 2023 Jul 14;29(14):2602-2611. doi: 10.1158/1078-0432.CCR-22-3282. Clin Cancer Res. 2023. PMID: 36799931
Eotaxin-2 and colorectal cancer: a potential target for immune therapy.
Cheadle EJ, Riyad K, Subar D, Rothwell DG, Ashton G, Batha H, Sherlock DJ, Hawkins RE, Gilham DE. Cheadle EJ, et al. Among authors: rothwell dg. Clin Cancer Res. 2007 Oct 1;13(19):5719-28. doi: 10.1158/1078-0432.CCR-07-1145. Clin Cancer Res. 2007. PMID: 17908961
Molecular analysis of single circulating tumour cells following long-term storage of clinical samples.
Mesquita B, Rothwell DG, Burt DJ, Chemi F, Fernandez-Gutierrez F, Slane-Tan D, Antonello J, Carter M, Carter L, Parry M, Franklin L, Marais R, Blackhall F, Dive C, Brady G. Mesquita B, et al. Among authors: rothwell dg. Mol Oncol. 2017 Dec;11(12):1687-1697. doi: 10.1002/1878-0261.12113. Epub 2017 Oct 24. Mol Oncol. 2017. PMID: 28741788 Free PMC article.
In silico error correction improves cfDNA mutation calling.
Kim CS, Mohan S, Ayub M, Rothwell DG, Dive C, Brady G, Miller C. Kim CS, et al. Among authors: rothwell dg. Bioinformatics. 2019 Jul 15;35(14):2380-2385. doi: 10.1093/bioinformatics/bty1004. Bioinformatics. 2019. PMID: 30520956 Free PMC article.
Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study.
Rothwell DG, Ayub M, Cook N, Thistlethwaite F, Carter L, Dean E, Smith N, Villa S, Dransfield J, Clipson A, White D, Nessa K, Ferdous S, Howell M, Gupta A, Kilerci B, Mohan S, Frese K, Gulati S, Miller C, Jordan A, Eaton H, Hickson N, O'Brien C, Graham D, Kelly C, Aruketty S, Metcalf R, Chiramel J, Tinsley N, Vickers AJ, Kurup R, Frost H, Stevenson J, Southam S, Landers D, Wallace A, Marais R, Hughes AM, Brady G, Dive C, Krebs MG. Rothwell DG, et al. Nat Med. 2019 May;25(5):738-743. doi: 10.1038/s41591-019-0380-z. Epub 2019 Apr 22. Nat Med. 2019. PMID: 31011204
Analysis of circulating cell-free DNA identifies KRAS copy number gain and mutation as a novel prognostic marker in Pancreatic cancer.
Mohan S, Ayub M, Rothwell DG, Gulati S, Kilerci B, Hollebecque A, Sun Leong H, Smith NK, Sahoo S, Descamps T, Zhou C, Hubner RA, McNamara MG, Lamarca A, Valle JW, Dive C, Brady G. Mohan S, et al. Among authors: rothwell dg. Sci Rep. 2019 Aug 12;9(1):11610. doi: 10.1038/s41598-019-47489-7. Sci Rep. 2019. PMID: 31406261 Free PMC article.
Profiling of Circulating Free DNA Using Targeted and Genome-wide Sequencing in Patients with SCLC.
Mohan S, Foy V, Ayub M, Leong HS, Schofield P, Sahoo S, Descamps T, Kilerci B, Smith NK, Carter M, Priest L, Zhou C, Carr TH, Miller C, Faivre-Finn C, Blackhall F, Rothwell DG, Dive C, Brady G. Mohan S, et al. Among authors: rothwell dg. J Thorac Oncol. 2020 Feb;15(2):216-230. doi: 10.1016/j.jtho.2019.10.007. Epub 2019 Oct 16. J Thorac Oncol. 2020. PMID: 31629061 Free PMC article.
71 results