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The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.
Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, Zacchigna S, Mukherjee S, Chen DJ, Mahmoud AI, Giacca M, Rabinovitch PS, Aroumougame A, Shah AM, Szweda LI, Sadek HA. Puente BN, et al. Among authors: rothermel ba. Cell. 2014 Apr 24;157(3):565-79. doi: 10.1016/j.cell.2014.03.032. Cell. 2014. PMID: 24766806 Free PMC article.
Sustained hemodynamic stress disrupts normal circadian rhythms in calcineurin-dependent signaling and protein phosphorylation in the heart.
Sachan N, Dey A, Rotter D, Grinsfelder DB, Battiprolu PK, Sikder D, Copeland V, Oh M, Bush E, Shelton JM, Bibb JA, Hill JA, Rothermel BA. Sachan N, et al. Among authors: rothermel ba. Circ Res. 2011 Feb 18;108(4):437-45. doi: 10.1161/CIRCRESAHA.110.235309. Epub 2011 Jan 13. Circ Res. 2011. PMID: 21233454 Free PMC article.
Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family.
Porrello ER, Mahmoud AI, Simpson E, Johnson BA, Grinsfelder D, Canseco D, Mammen PP, Rothermel BA, Olson EN, Sadek HA. Porrello ER, et al. Among authors: rothermel ba. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):187-92. doi: 10.1073/pnas.1208863110. Epub 2012 Dec 17. Proc Natl Acad Sci U S A. 2013. PMID: 23248315 Free PMC article.
Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis.
Rotter D, Peiris H, Grinsfelder DB, Martin AM, Burchfield J, Parra V, Hull C, Morales CR, Jessup CF, Matusica D, Parks BW, Lusis AJ, Nguyen NUN, Oh M, Iyoke I, Jakkampudi T, McMillan DR, Sadek HA, Watt MJ, Gupta RK, Pritchard MA, Keating DJ, Rothermel BA. Rotter D, et al. Among authors: rothermel ba. EMBO Rep. 2018 Dec;19(12):e44706. doi: 10.15252/embr.201744706. Epub 2018 Nov 2. EMBO Rep. 2018. PMID: 30389725 Free PMC article.
A calcineurin-Hoxb13 axis regulates growth mode of mammalian cardiomyocytes.
Nguyen NUN, Canseco DC, Xiao F, Nakada Y, Li S, Lam NT, Muralidhar SA, Savla JJ, Hill JA, Le V, Zidan KA, El-Feky HW, Wang Z, Ahmed MS, Hubbi ME, Menendez-Montes I, Moon J, Ali SR, Le V, Villalobos E, Mohamed MS, Elhelaly WM, Thet S, Anene-Nzelu CG, Tan WLW, Foo RS, Meng X, Kanchwala M, Xing C, Roy J, Cyert MS, Rothermel BA, Sadek HA. Nguyen NUN, et al. Among authors: rothermel ba. Nature. 2020 Jun;582(7811):271-276. doi: 10.1038/s41586-020-2228-6. Epub 2020 Apr 22. Nature. 2020. PMID: 32499640 Free PMC article.
Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy.
Tannous P, Zhu H, Nemchenko A, Berry JM, Johnstone JL, Shelton JM, Miller FJ Jr, Rothermel BA, Hill JA. Tannous P, et al. Among authors: rothermel ba. Circulation. 2008 Jun 17;117(24):3070-8. doi: 10.1161/CIRCULATIONAHA.107.763870. Epub 2008 Jun 9. Circulation. 2008. PMID: 18541737 Free PMC article.
104 results