Rosal R - Search Results

1

PNC-27, a Chimeric p53-Penetratin Peptide Binds to HDM-2 in a p53 Peptide-like Structure, Induces Selective Membrane-Pore Formation and Leads to Cancer Cell Lysis.

Sarafraz-Yazdi E, Mumin S, Cheung D, Fridman D, Lin B, Wong L, Rosal R, Rudolph R, Frenkel M, Thadi A, Morano WF, Bowne WB, Pincus MR, Michl J. Sarafraz-Yazdi E, et al. Among authors: rosal r. Biomedicines. 2022 Apr 20;10(5):945. doi: 10.3390/biomedicines10050945. Biomedicines. 2022. PMID: 35625682 Free PMC article.

2

Common conformational effects of p53 mutations.

Chen JM, Rosal R, Smith S, Pincus MR, Brandt-Rauf PW. Chen JM, et al. Among authors: rosal r. J Protein Chem. 2001 Feb;20(2):101-5. doi: 10.1023/a:1011065022283. J Protein Chem. 2001. PMID: 11563689

3

Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells.

Kanovsky M, Raffo A, Drew L, Rosal R, Do T, Friedman FK, Rubinstein P, Visser J, Robinson R, Brandt-Rauf PW, Michl J, Fine RL, Pincus MR. Kanovsky M, et al. Among authors: rosal r. Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12438-43. doi: 10.1073/pnas.211280698. Epub 2001 Oct 16. Proc Natl Acad Sci U S A. 2001. PMID: 11606716 Free PMC article.

4

Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site.

Do TN, Rosal RV, Drew L, Raffo AJ, Michl J, Pincus MR, Friedman FK, Petrylak DP, Cassai N, Szmulewicz J, Sidhu G, Fine RL, Brandt-Rauf PW. Do TN, et al. Among authors: rosal rv. Oncogene. 2003 Mar 13;22(10):1431-44. doi: 10.1038/sj.onc.1206258. Oncogene. 2003. PMID: 12629507

5

NMR solution structure of a peptide from the mdm-2 binding domain of the p53 protein that is selectively cytotoxic to cancer cells.

Rosal R, Pincus MR, Brandt-Rauf PW, Fine RL, Michl J, Wang H. Rosal R, et al. Biochemistry. 2004 Feb 24;43(7):1854-61. doi: 10.1021/bi035718g. Biochemistry. 2004. PMID: 14967026

6

Computational protein chemistry of p53 and p53 peptides.

Brandt-Rauf PW, Rosal RV, Fine RL, Pincus MR. Brandt-Rauf PW, et al. Among authors: rosal rv. Front Biosci. 2004 Sep 1;9:2778-87. doi: 10.2741/1435. Front Biosci. 2004. PMID: 15353313 Review.

7

The role of alpha-helical structure in p53 peptides as a determinant for their mechanism of cell death: necrosis versus apoptosis.

Rosal R, Brandt-Rauf P, Pincus MR, Wang H, Mao Y, Li Y, Fine RL. Rosal R, et al. Adv Drug Deliv Rev. 2005 Feb 28;57(4):653-60. doi: 10.1016/j.addr.2004.10.008. Epub 2005 Jan 8. Adv Drug Deliv Rev. 2005. PMID: 15722169 Review.

8

Conformational effects of a common codon 399 polymorphism on the BRCT1 domain of the XRCC1 protein.

Monaco R, Rosal R, Dolan MA, Pincus MR, Brandt-Rauf PW. Monaco R, et al. Among authors: rosal r. Protein J. 2007 Dec;26(8):541-6. doi: 10.1007/s10930-007-9095-y. Protein J. 2007. PMID: 17899335

9

Conformational effects of a common codon 751 polymorphism on the C-terminal domain of the xeroderma pigmentosum D protein.

Monaco R, Rosal R, Dolan MA, Pincus MR, Freyer G, Brandt-Rauf PW. Monaco R, et al. Among authors: rosal r. J Carcinog. 2009;8:12. doi: 10.4103/1477-3163.54918. J Carcinog. 2009. PMID: 19661678 Free PMC article.

10

C-Terminal p53 Palindromic Tetrapeptide Restores Full Apoptotic Function to Mutant p53 Cancer Cells In Vitro and In Vivo.

Fine RL, Mao Y, Dinnen R, Rosal RV, Raffo A, Hochfeld U, Senatus P, Bruce JN, Nichols G, Wang H, Li Y, Brandt-Rauf PW. Fine RL, et al. Among authors: rosal rv. Biomedicines. 2023 Jan 5;11(1):137. doi: 10.3390/biomedicines11010137. Biomedicines. 2023. PMID: 36672645 Free PMC article.

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