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Pharmacological modulation of vascular ageing: A review from VascAgeNet.
Roth L, Dogan S, Tuna BG, Aranyi T, Benitez S, Borrell-Pages M, Bozaykut P, De Meyer GRY, Duca L, Durmus N, Fonseca D, Fraenkel E, Gillery P, Giudici A, Jaisson S, Johansson M, Julve J, Lucas-Herald AK, Martinet W, Maurice P, McDonnell BJ, Ozbek EN, Pucci G, Pugh CJA, Rochfort KD, Roks AJM, Rotllan N, Shadiow J, Sohrabi Y, Spronck B, Szeri F, Terentes-Printzios D, Tunc Aydin E, Tura-Ceide O, Ucar E, Yetik-Anacak G. Roth L, et al. Among authors: roks ajm. Ageing Res Rev. 2023 Dec;92:102122. doi: 10.1016/j.arr.2023.102122. Epub 2023 Nov 11. Ageing Res Rev. 2023. PMID: 37956927 Free article. Review.
Ercc1 DNA repair deficiency results in vascular aging characterized by VSMC phenotype switching, ECM remodeling, and an increased stress response.
van der Linden J, Stefens SJM, Heredia-Genestar JM, Ridwan Y, Brandt RMC, van Vliet N, de Beer I, van Thiel BS, Steen H, Cheng C, Roks AJM, Danser AHJ, Essers J, van der Pluijm I. van der Linden J, et al. Among authors: roks ajm. Aging Cell. 2024 Mar 7:e14126. doi: 10.1111/acel.14126. Online ahead of print. Aging Cell. 2024. PMID: 38451018 Free article.
Model Systems to Study the Mechanism of Vascular Aging.
van der Linden J, Trap L, Scherer CV, Roks AJM, Danser AHJ, van der Pluijm I, Cheng C. van der Linden J, et al. Among authors: roks ajm. Int J Mol Sci. 2023 Oct 19;24(20):15379. doi: 10.3390/ijms242015379. Int J Mol Sci. 2023. PMID: 37895059 Free PMC article. Review.
DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice.
de Boer M, Te Lintel Hekkert M, Chang J, van Thiel BS, Martens L, Bos MM, de Kleijnen MGJ, Ridwan Y, Octavia Y, van Deel ED, Blonden LA, Brandt RMC, Barnhoorn S, Bautista-Niño PK, Krabbendam-Peters I, Wolswinkel R, Arshi B, Ghanbari M, Kupatt C, de Windt LJ, Danser AHJ, van der Pluijm I, Remme CA, Stoll M, Pothof J, Roks AJM, Kavousi M, Essers J, van der Velden J, Hoeijmakers JHJ, Duncker DJ. de Boer M, et al. Among authors: roks ajm. Aging Cell. 2023 Mar;22(3):e13768. doi: 10.1111/acel.13768. Epub 2023 Feb 8. Aging Cell. 2023. PMID: 36756698 Free PMC article.
Soluble guanylate cyclase activator BAY 54-6544 improves vasomotor function and survival in an accelerated ageing mouse model.
Ataei Ataabadi E, Golshiri K, Jüttner AA, de Vries R, Van den Berg-Garrelds I, Nagtzaam NMA, Khan HN, Leijten FPJ, Brandt RMC, Dik WA, van der Pluijm I, Danser AHJ, Sandner P, Roks AJM. Ataei Ataabadi E, et al. Among authors: roks ajm. Aging Cell. 2022 Sep;21(9):e13683. doi: 10.1111/acel.13683. Epub 2022 Aug 27. Aging Cell. 2022. PMID: 36029161 Free PMC article.
Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study.
Portilla-Fernandez E, Klarin D, Hwang SJ, Biggs ML, Bis JC, Weiss S, Rospleszcz S, Natarajan P, Hoffmann U, Rogers IS, Truong QA, Völker U, Dörr M, Bülow R, Criqui MH, Allison M, Ganesh SK, Yao J, Waldenberger M, Bamberg F, Rice KM, Essers J, Kapteijn DMC, van der Laan SW, de Knegt RJ, Ghanbari M, Felix JF, Ikram MA, Kavousi M, Uitterlinden AG, Roks AJM, Danser AHJ, Tsao PS, Damrauer SM, Guo X, Rotter JI, Psaty BM, Kathiresan S, Völzke H, Peters A, Johnson C, Strauch K, Meitinger T, O'Donnell CJ, Dehghan A; VA Million Veteran Program. Portilla-Fernandez E, et al. Among authors: roks ajm. Hum Mol Genet. 2022 Oct 10;31(20):3566-3579. doi: 10.1093/hmg/ddac051. Hum Mol Genet. 2022. PMID: 35234888 Free PMC article.
76 results