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Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy.
Kober C, Roewe J, Schmees N, Roese L, Roehn U, Bader B, Stoeckigt D, Prinz F, Gorjánácz M, Roider HG, Olesch C, Leder G, Irlbacher H, Lesche R, Lefranc J, Oezcan-Wahlbrink M, Batra AS, Elmadany N, Carretero R, Sahm K, Oezen I, Cichon F, Baumann D, Sadik A, Opitz CA, Weinmann H, Hartung IV, Kreft B, Offringa R, Platten M, Gutcher I. Kober C, et al. Among authors: roewe j. J Immunother Cancer. 2023 Nov;11(11):e007495. doi: 10.1136/jitc-2023-007495. J Immunother Cancer. 2023. PMID: 37963637 Free PMC article.
Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFβ1 and IL-27.
Riehl DR, Sharma A, Roewe J, Murke F, Ruppert C, Eming SA, Bopp T, Kleinert H, Radsak MP, Colucci G, Subramaniam S, Reinhardt C, Giebel B, Prinz I, Guenther A, Strand D, Gunzer M, Waisman A, Ward PA, Ruf W, Schäfer K, Bosmann M. Riehl DR, et al. Among authors: roewe j. Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2215421120. doi: 10.1073/pnas.2215421120. Epub 2023 Sep 27. Proc Natl Acad Sci U S A. 2023. PMID: 37756334 Free PMC article.
Alzheimer's disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss.
Popescu AS, Butler CA, Allendorf DH, Piers TM, Mallach A, Roewe J, Reinhardt P, Cinti A, Redaelli L, Boudesco C, Pradier L, Pocock JM, Thornton P, Brown GC. Popescu AS, et al. Among authors: roewe j. Glia. 2023 Apr;71(4):974-990. doi: 10.1002/glia.24318. Epub 2022 Dec 8. Glia. 2023. PMID: 36480007 Free PMC article.
Novel potent liposome agonists of triggering receptor expressed on myeloid cells 2 phenocopy antibody treatment in cells.
Boudesco C, Nonneman A, Cinti A, Picardi P, Redaelli L, Swijsen S, Roewe J, Reinhardt P, Ibach M, Walter J, Pocock JM, Ren Y, Driguez PA, Dargazanli G, Eyquem S, Proto J, Flores-Morales A, Pradier L. Boudesco C, et al. Among authors: roewe j. Glia. 2022 Dec;70(12):2290-2308. doi: 10.1002/glia.24252. Epub 2022 Aug 1. Glia. 2022. PMID: 35912412 Free PMC article.
Bacterial polyphosphates interfere with the innate host defense to infection.
Roewe J, Stavrides G, Strueve M, Sharma A, Marini F, Mann A, Smith SA, Kaya Z, Strobl B, Mueller M, Reinhardt C, Morrissey JH, Bosmann M. Roewe J, et al. Nat Commun. 2020 Aug 12;11(1):4035. doi: 10.1038/s41467-020-17639-x. Nat Commun. 2020. PMID: 32788578 Free PMC article.
Neuroendocrine Modulation of IL-27 in Macrophages.
Roewe J, Higer M, Riehl DR, Gericke A, Radsak MP, Bosmann M. Roewe J, et al. J Immunol. 2017 Oct 1;199(7):2503-2514. doi: 10.4049/jimmunol.1700687. Epub 2017 Aug 23. J Immunol. 2017. PMID: 28835457
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